Results 91 to 100 of about 10,081 (286)
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Botanical tree reconstruction from a single image via 3D GAN-based skeletonization
Virtual Reality & Intelligent HardwareBackground: 3D botanical tree reconstruction from a single image plays a vital role in the field of computer graphics. However, accurately capturing the intricate branching patterns and detailed morphologies of trees remains a challenge. Methods: In this
Chi Weng, MA +3 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Materials & DesignThe work proposes an image segmentation algorithm that isolates slender regions in three-dimensional microstructures. Characterizing slender regions in material microstructures is an extremely important aspect in material science because these regions ...
Vinit Vijay Deshpande, Romana Piat
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers +7 more
wiley +1 more source
3D THINNING AND ITS APPLICATIONS TO MEDICAL IMAGE PROCESSING
TASK Quarterly, 1999 Skeleton is a frequently used feature to represent general form of an object. The importance of that region-based shape feature shows an upward tendency in medical image processing, too.
KALMAN PALAGYI +3 more
doaj
Colon centreline calculation for CT colonography using optimised 3D opological thinning [PDF]
, 2002 CT colonography is an emerging technique for colorectal cancer screening. This technique facilitates noninvasive imaging of the colon interior by generating virtual reality models of the colon lumen.
Sadleir, Robert J.T., Whelan, Paul F.
core
Sex Differences in Medication Discontinuation in Axial Spondyloarthritis
Arthritis Care &Research, EarlyView.Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall +9 more
wiley +1 more source
Focused Proofreading: Efficiently Extracting Connectomes from Segmented EM Images [PDF]
, 2014 Identifying complex neural circuitry from electron microscopic (EM) images may help unlock the mysteries of the brain. However, identifying this circuitry requires time-consuming, manual tracing (proofreading) due to the size and intricacy of these image
Plaza, Stephen M.
core
Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome
Arthritis Care &Research, EarlyView.Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino +9 more
wiley +1 more source