Results 71 to 80 of about 621,417 (312)
2-Fluoro-N-methyl-N-{[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methyl}ethanamine
Starting from N-methyl-1-[(3S*,4S*)-4-(2-methylphenoxy)-3,4-dihydro-1H-isochromen-3-yl]methanamine (1) target compound 2 is prepared in a mild, direct alkylation approach with 2-fluoroethyl trifluoromethanesulfonate.
Catharina Neudorfer +6 more
doaj +1 more source
Medical images synthesis is useful to address persistent issues such as the lack of training data diversity and inflexibility of traditional data augmentation faced by medical image analysis researchers when developing their deep learning models ...
Hong-Seng Gan +4 more
doaj +1 more source
On the Diversity of Realistic Image Synthesis
10 pages, 11 ...
Zichen Yang +2 more
openaire +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Objective: Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a sensitive imaging technique critical for breast cancer diagnosis. However, the administration of contrast agents poses a potential risk. This can be avoided if contrast-
Eunjin Kim +5 more
doaj +1 more source
Freestyle Layout-to-Image Synthesis
Accepted to CVPR ...
Han Xue +4 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Multi-resolution, multi-sensor image fusion: general fusion framework
Multi-resolution image fusion also known as pansharpening aims to include spatial information from a high resolution image, e.g. panchromatic or Synthetic Aperture Radar (SAR) image, into a low resolution image, e.g.
Palubinskas, Gintautas +3 more
core +1 more source
S.1809-1812Depth-image-based rendering (DIBR) is used to generate additional views of a real-world scene from images or videos and associated per-pixel depth information.
Köppel, M. +6 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

