Results 51 to 60 of about 587,374 (265)

Exemplar-Based Sketch Colorization with Cross-Domain Dense Semantic Correspondence

Mathematics, 2022
This paper aims to solve the task of coloring a sketch image given a ready-colored exemplar image. Conventional exemplar-based colorization methods tend to transfer styles from reference images to grayscale images by employing image analogy techniques or
Jinrong Cui, Haowei Zhong, Hailong Liu, Yulu Fu   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Multi-Style Unsupervised Image Synthesis Using Generative Adversarial Nets

IEEE Access, 2021
Unsupervised cross-domain image-to-image translation is a very active topic in computer vision and graphics. This task has two challenges: 1) lack of paired training data and 2) numerous possible outputs from a single image.
Guoyun Lv, Syed Muhammad Israr, Shengyong Qi   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

1-(3-Amino-1-phenylpropyl)-3-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one

Molbank, 2015
Starting from 1-(2-fluorophenyl)-1,3-dihydro-2H-benzimidazol-2-one (1) and (1-bromo-3-chloropropyl)benzene (2), the target compound 3, which represents a precursor for future radiolabeling, is prepared in a three-step synthesis.
Catharina Neudorfer, Nadine Eberherr, Karem Shanab, Wolfgang Holzer, Christina Rami-Mark, Markus Mitterhauser, Wolfgang Wadsak, Helmut Spreitzer   +7 more
doaj   +1 more source

Hierarchical Knee Image Synthesis Framework for Generative Adversarial Network: Data From the Osteoarthritis Initiative

IEEE Access, 2022
Medical images synthesis is useful to address persistent issues such as the lack of training data diversity and inflexibility of traditional data augmentation faced by medical image analysis researchers when developing their deep learning models ...
Hong-Seng Gan, Muhammad Hanif Ramlee, Bander Ali Saleh Al-Rimy, Yeng-Seng Lee, Prayoot Akkaraekthalin   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tumor-Attentive Segmentation-Guided GAN for Synthesizing Breast Contrast-Enhanced MRI Without Contrast Agents

IEEE Journal of Translational Engineering in Health and Medicine, 2023
Objective: Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a sensitive imaging technique critical for breast cancer diagnosis. However, the administration of contrast agents poses a potential risk. This can be avoided if contrast-
Eunjin Kim, Hwan-Ho Cho, Junmo Kwon, Young-Tack Oh, Eun Sook Ko, Hyunjin Park   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source