Results 121 to 130 of about 409,949 (303)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Corticospinal facilitation during motor imagery
, 2010 This chapter summarises the evidence for primary motor cortex engagement during motor imagery. The corticospinal system is facilitated in a muscle- and temporally-specific way during explicit motor imagery, particularly when a kinaesthetic imagery ...
Stinear, Cathy, Cathy M. Stinear
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Assessment of the CORONA series of satellite imagery for landscape archaeology: a case study from the Orontes valley, Syria [PDF]
, 2004 In 1995, a large database of satellite imagery with worldwide coverage taken from 1960 until 1972 was declassified. The main advantages of this imagery known as CORONA that made it attractive for archaeology were its moderate cost and its historical ...
Galiatsatos, Nikolaos
core
Using imagery to solve spatial problems
, 1998 This report focuses on the use of imagery to solve a range of spatial problems. The research projects reviewed in this report offer some insight into the range of strategies used by solvers of spatial problems and point to relationships between spatial ...
O'Driscoll-Tole, Kim +2 more
core +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Investigating The Influence Of Attentiveness On Motor Imagery Performance
, 2023 Although much research has focused on motor imagery, the mental rehearsal of movement, little has examined the influence cognitive deficits have on its performance.
Green, Darby
core