Results 91 to 100 of about 2,406,635 (289)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
IMAGES IN CLINICAL MEDICINE. Tracheobronchomegaly. [PDF]
, 2016 Casso, G., Schoettker, P.
core +2 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Investigation of the effectiveness of no-reference metric in image evaluation in nuclear medicine.
PLoS ONEBackgroundIn nuclear medicine, normalized mean square error (NMSE) is widely used for image quality evaluation and machine adjustment. However, evaluating clinical images in nuclear medicine using NMSE necessitates acquiring a reference image, which is ...
Shigeaki Higashiyama +7 more
doaj +1 more source
Images in clinical medicine. Chromoblastomycosis. [PDF]
, 2005 Brown, Michael, Pasvol, Geoffrey
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Images in Emergency Medicine: Left Atrial Myxoma
Western Journal of Emergency Medicine, 2008 This visual diagnosis case summary presents the case of a 64 year old male who presented with right lower quadrant abdominal pain and who was subsequently found to have a very large left sided atrial myxoma.
Darracq, Michael A
doaj
Images in Medicine - An Atypical Presentation of Unilateral Tongue Angioedema Caused by Acetaminophen. [PDF]
J Clin Diagn Res, 2017 Deepthi A +4 more
europepmc +1 more source