Results 31 to 40 of about 76,645 (266)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
eTropic: electronic journal of studies in the tropics, 2013 This paper opens with a historical survey of the imaginary representation of islands in Western literature and then proceeds to a selective account of the island imaginary in largely ‘middlebrow’ writings and photography about the tropics.
Stephen Torre
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Polar Mediterranean Imaginary. A Renewed Paradigm by Vilhjalmur Stefansson
Nordicum-MediterraneumSouthern social imaginaries have typically conceived of the North as a frozen and inhospitable area, depriving it of much interest. However, during the first part of the 20th century, the anthropologist and explorer Vilhjalmur Stefansson unveiled many ...
Santiago Villalobos Dantas
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A cidade imaginada ou o imaginário da cidade The city imagined, or the city’s imaginary
História, Ciências, Saúde: Manguinhos, 1998 O artigo trata da temática da cidade real-cidade imaginária. Argumenta que, ao refletirmos sobre a cidade, refletimos, também, sobre nós mesmos, com todos os nossos sonhos, frustrações, ansiedades e esperanças.
Maria Aparecida Lopes Nogueira
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Imaginary and Symbolic Forms of Water between Spirit and Culture
Academicus International Scientific JournalWater is a theme connected to human and social development, not only biologically but also in terms of cultural and identity processes; surprisingly, studies that discuss water from a sociocultural/sociological perspective are scarce.
Eleonora Sparano, Nicola Strizzolo
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ReS Futurae, 2018 Science-fiction and the imaginary of cosmos bring a fertile framework to video games. Apart the depth of the fictional worlds that it allows to develop, Space void as a narrative and iconographic trope opens a wide variety of issues linked to the ...
Guillaume Baychelier
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source