Results 41 to 50 of about 217,674 (248)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Imaginary and Symbolic Forms of Water between Spirit and Culture
Academicus International Scientific JournalWater is a theme connected to human and social development, not only biologically but also in terms of cultural and identity processes; surprisingly, studies that discuss water from a sociocultural/sociological perspective are scarce.
Eleonora Sparano, Nicola Strizzolo
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
[Imaginary Landscapes Student Demos 32]
, 2003 Wet on wet landscape in blue. On same sheet as [Imaginary Landscapes Student Demos 33]Tiff file: 3330x2110 pixels, 20.6 Mb; Display: jpeg, 519x800 pixels ...
Father Edward Catich
core +1 more source
Bulletin de l’Association de Géographes FrançaisSaint-Étienne, an industrial stronghold until 1918 before becoming an area in crisis, has drawn its roots and its identity from its underground. Today, its landscape reveals not only the traces of this unique industrial epic, but also the signs of its ...
Georges-Henry Laffont, Luc Rojas
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
[Imaginary Landscapes Student Demos 40]
, 2003 Wet on wet landscape in black and pink. On same sheet as [Imaginary Landscapes Student Demos 41]Tiff file: 3270x1810 pixels, 16.9 Mb; Display: jpeg, 443x800 pixels ...
Father Edward Catich
core +1 more source
Communication and Identity: An Approximation to the Study of Consumption [PDF]
Universitas Humanística, 2007 To talk about consumer culture is to question the role that capitalist exchange, objects and their dynamics play in today’s world. To understand consumption as an action of meaning and as a problem of anthropological concern brings about valuable data ...
Claudia Constanza Méndez Hernández
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
[Imaginary Landscapes Student Demos 33]
, 2003 Wet on wet landscape in blue. On same sheet as [Imaginary Landscapes Student Demos 32]Tiff file: 3320x1850 pixels, 17.6 Mb; Display: jpeg, 446x800 pixels ...
Father Edward Catich
core +1 more source