Results 51 to 60 of about 79,358 (268)
Organization StudiesDifferent theoretical conceptualizations of ‘imaginaries’ are being offered as tractable responses to the ascending organizational challenge known as ‘the future’. Despite their undoubted promise, however, the plurality of conceptualizations of ‘imaginaries’ makes it unclear how the term is contributing to impactful theory.
Daniel Aditya Tjhin, Annika Skoglund
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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Ergo, an Open Access Journal of Philosophy, 2018 Our senses provide us with information about the world, but what exactly do they tell us? I argue that in order to optimally respond to sensory stimulations, an agent’s doxastic space may have an extra, “imaginary”dimension of possibility; perceptual experiences confer certainty on propositions in this dimension.
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
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The Polar Mediterranean Imaginary. A Renewed Paradigm by Vilhjalmur Stefansson
Nordicum-MediterraneumSouthern social imaginaries have typically conceived of the North as a frozen and inhospitable area, depriving it of much interest. However, during the first part of the 20th century, the anthropologist and explorer Vilhjalmur Stefansson unveiled many ...
Santiago Villalobos Dantas
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A cidade imaginada ou o imaginário da cidade The city imagined, or the city’s imaginary
História, Ciências, Saúde: Manguinhos, 1998 O artigo trata da temática da cidade real-cidade imaginária. Argumenta que, ao refletirmos sobre a cidade, refletimos, também, sobre nós mesmos, com todos os nossos sonhos, frustrações, ansiedades e esperanças.
Maria Aparecida Lopes Nogueira
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
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ReS Futurae, 2018 Science-fiction and the imaginary of cosmos bring a fertile framework to video games. Apart the depth of the fictional worlds that it allows to develop, Space void as a narrative and iconographic trope opens a wide variety of issues linked to the ...
Guillaume Baychelier
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Imaginary and Symbolic Forms of Water between Spirit and Culture
Academicus International Scientific JournalWater is a theme connected to human and social development, not only biologically but also in terms of cultural and identity processes; surprisingly, studies that discuss water from a sociocultural/sociological perspective are scarce.
Eleonora Sparano, Nicola Strizzolo
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