Results 71 to 80 of about 79,358 (268)
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
L’immaginario politico delle memorie: Brasile 1964-1985 [PDF]
Diacronie. Studi di Storia Contemporanea, 2016 From the numerous forms of symbolic good produced in Brazil and pertaining to the period of the dictatorship, itself a stimulus for political commemoration and constant subject of debate, we have chosen to concentrate on the analysis of books, considered
Lucileide Costa Cardoso
doaj
Time and chaos: the “imagination of possibilities” and the media
Comunicação e Sociedade, 2019 This article proposes a reflection about the notion of time and its relation to the media based on the complex thinking paradigm and the transdisciplinary perspective.
Gustavo Castro, Florence Dravet
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
FEBS Open Bio, EarlyView.Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Im@go. A Journal of the Social Imaginary, 2022 Sacred and imaginary. The paper aims to investigate the relationship between the imaginary and the sacred, from the point of view of the dialectic between the imaginary and society.
Domenico Secondulfo
doaj
Être « Quiddkid » : l'engagement des joueurs dans une pratique alternative
Sciences du Jeu, 2018 Quidditch is a contemporary leisure activity based on the wizard sport from the Harry Potter saga. Created 12 years ago, this activity deals with the motivations of the players, called “quiddkids”.
Audrey Tuaillon Demésy
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source