Results 91 to 100 of about 215,997 (243)

Imagination as Primordial Faculty in Ethichs a Fichtean Approach

open access: yes, 2018
In late eighteenth and early nineteenth century imagination has gained a respectable place in philosophy that it has not have before. Unlike previous philosophers, Immanuel Kant could be named as the one who initiated it, since in the first edition of ...
Salman, Selda
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Imagine an Imageless Imagination

open access: yes, 2017
A trend in contemporary discussion pertaining to the imagination has attempted to theoretically conceptualise a type of qualia-free imagination, commonly referred to as propositional imagination. This paper argues that an act of imagination cannot be an act of imagination without both cognitive and sensory phenomenology.
openaire   +4 more sources

Imagination, creativity, and aphantasia

open access: yes
This chapter focuses on the role of the imagination in creativity, using aphantasia as a case study. It first distinguishes between imagination and mental imagery, before giving an overview of what we know about aphantasia to date, focusing in particular
Blomkvist, Andrea
core   +5 more sources

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

The role of the imagination in Hume's science of man [PDF]

open access: yes, 2012
In recent years there has been an explosion of writing on David Hume. His scepticism, his writings on morality, politics, and religion, have all received substantial attention.
Bernard, Christopher
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Amalie Skrams Jamaica

open access: yesEdda
Hva slags Jamaica er det Amalie Skram presenterer for oss i romanen To venner (1887), og hvordan skal dagens lesere fortolke denne stedsfremstillingen på en bevisst og tekstkritisk måte?
Anders Skare Malvik
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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