Results 111 to 120 of about 179,692 (309)

Imagining Unequals, Imagining Equals

, 2022
Why did »equality« become prominent in European societies based on hierarchy during the Enlightenment? What does »equality« imply for societies, politics or legal systems? The contributors explore concepts of equality from the perspectives of history and law and draw on the idea that practices of comparing were essential when it came to imagining ...
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Creative imagination

, 2017
In this chapter I look at the links between collective memory and the imagination of collective futures. Drawing on works on imagination and autobiographical memory, I first discuss the role of past experiences in imagining the future. I then explore the
Karwowski, Maciej, Glăveanu, Vlad Petre, de Saint Laurent, Constance, Jankowska, Dorota M.   +3 more
core  

The Relationship between Imagination and Knowledge in MullaSadra’s Philosophy [PDF]

حکمت صدرایی, 2018
In this study, we try to show a pattern of philosophical view of Mulla Sadra about the relationship between imagination and knowledge based on an analytic methodology.
sayed mahdi mirhadi, Hasan Ali Bakhtyar Nasr Abadi, Mohammad Najafi   +2 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

(Creatures of imagination : on dreams and the radical imagination)

, 2015
This paper is driven by the conviction that the imagination names a field that far exceeds anything able to be spoken of as a power, a faculty, or something at our disposal.
Schmidt, Dennis J. (R18285)
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

All the pieces matter: discovering moral imagination along the wire [PDF]

, 2014
: This dissertation is an investigation into the tool of moral imagination in the service of social justice. Supported by the philosophies of David Purpel, Maxine Greene, and John Dewey, this analysis is engaged through six themes examined through the ...
Solér, Michelle Lowe, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

“A Pinch of Imagination”

Lateral
There is a rise in events connecting people to food, the sources of food, and the materiality of food––including all its affective and sensorial qualities.
Paulina Lanz, Sulafa Zidani
doaj   +1 more source