Results 161 to 170 of about 179,692 (309)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Seeing/Scene-ing Imagination in Virginia Woolf’s “Nurse Lugton’s Curtain”

open access: yes
This paper argues that Sir Thomas Browne’s ruminations on the dialectics between life and death, wakefulness and sleep in his books might have influenced Virginia Woolf when she wrote the “Nurse Lugton’s Curtain.” This short story might not be as playful
Kuo, Chia-chen
core   +1 more source

Decoupling simultaneous motor imagination and execution via orthogonal ECoG neural representations. [PDF]

open access: yesNat Commun
Pollina L   +9 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Fantasy control [Elektronisk resurs] : Implications for distributed imagination and affect attunement in music and sound

open access: yes, 2019
This chapter deals with the control of imagination. Three thematically distinct aspects of sonic imagination are investigated – archive, context, and identification – together with two modes of connection with the environment – metaphorical projection ...
Volgsten, Ulrik,
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

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