Results 201 to 210 of about 179,692 (309)

Housing the Environmental Imagination Politics, Beauty, and Refuge in American Nature Writing

The last few decades have seen an explosion of interest in literature and the sense of place. Many essays, books and presentations have explored the aesthetics, politics, and urgency of understanding and appreciating the unique qualities of coasts ...
Quigley, Peter.
core  

Evaluating image modification as a harm reduction approach in content moderation. [PDF]

Psychol Res
Lewitzka S, Liebeknecht A, Bridgland VME, Moeck EK, Nixon RDV, Semmler C, Takarangi MKT.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Cognitive architecture and behavioral model based on social evidence and resource constraints. [PDF]

Brain Inform
Kolonin A.
europepmc   +1 more source

Investigating the Influence of Role-Playing on Empathy and Perspective-Taking by Analyzing Level of Engagement, Emotional, and Cognitive Processes Through a Word Count Analysis Approach. [PDF]

Perspect Med Educ
Tien YM, Lin CY, Pai PY, Tsai CH, Hsu LC.   +4 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Applying sequences of combinations of movements based on motor development stages principles to elite athletes: conceptual foundations and testable hypothese. [PDF]

Front Sports Act Living
Msaidie H, Gomez-Merino D, Chennaoui M.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Practice of Active Waiting: Leadership Education Curricula in Uncertain Times. [PDF]

New Dir Stud Leadersh
Roland E, Wiborg ER.
europepmc   +1 more source