Results 41 to 50 of about 1,177,243 (298)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Quantitative volumetric Raman imaging of three dimensional cell cultures

open access: yesNature Communications, 2017
Advances in chemical imaging capability can add to our understanding of complex cellular systems. Here the authors develop a framework for label-free quantitative volumetric Raman spectroscopic imaging and use it to visualize and quantify biomolecules in
Charalambos Kallepitis   +6 more
doaj   +1 more source

Three-dimensional imaging of Drosophila melanogaster.

open access: yesPLoS ONE, 2007
BackgroundThe major hindrance to imaging the intact adult Drosophila is that the dark exoskeleton makes it impossible to image through the cuticle. We have overcome this obstacle and describe a method whereby the internal organs of adult Drosophila can ...
Leeanne McGurk   +4 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Three‐dimensional imaging of upper esophageal sphincter resting pressure

open access: yesLaryngoscope Investigative Otolaryngology, 2019
Objective High‐resolution manometry (HRM) is used to analyze upper esophageal sphincter (UES) physiology. Conventional HRM can yield imprecise measurements of UES resting pressure given its unidirectional sensors and averaging of circumferential pressure.
Shun‐ichi Chitose   +6 more
doaj   +1 more source

Three-dimensional Imaging of Microstructure in Gold Nanocrystals [PDF]

open access: yes, 2003
X-ray diffraction using a coherent beam involves the mutual interference among all the extremities of small crystals. The continuous diffraction pattern so produced can be phased because it can be oversampled.
Pfeifer, MA   +3 more
core  

Observational Approaches to the Topology of the Universe [PDF]

open access: yes, 2000
Many different and complementary strategies for translating the basic principle of multiple topological imaging into observational analysis are now available, both for three-dimensional and two-dimensional catalogues.Comment: very compact, (2 page) write-
Roukema, Boudewijn F.
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Determination of 3D Trajectories of Knots in Solar Prominences Using MSDP Data [PDF]

open access: yes, 2010
In this paper we present a new method of restoration of the true thee-dimensional trajectories of the prominence knots based on ground-based observations taken with a single telescope, which is equipped with a Multi-Channel Subtractive Double Pass ...
A. Bemporad   +17 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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