Results 51 to 60 of about 15,179,697 (302)

Quantitative volumetric Raman imaging of three dimensional cell cultures

Nature Communications, 2017
Advances in chemical imaging capability can add to our understanding of complex cellular systems. Here the authors develop a framework for label-free quantitative volumetric Raman spectroscopic imaging and use it to visualize and quantify biomolecules in
Charalambos Kallepitis, Mads S. Bergholt, Manuel M. Mazo, Vincent Leonardo, Stacey C. Skaalure, Stephanie A. Maynard, Molly M. Stevens   +6 more
doaj   +1 more source

Application of multi ⁃modal image fusion three ⁃dimensional reconstruction technology in operation of meningioma in the central area of the brain

Chinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To explore the application value of multi ⁃ modal image fusion three ⁃ dimensional (3D) reconstruction technology in operation of meningioma in the central area. Methods and Results Using multi⁃modal image fusion 3D reconstruction technology to
MA Long⁃tao, ZHANG Wei⁃wen, MEI Jia⁃ming, NIU Chao⁃shi   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Three‐dimensional imaging of upper esophageal sphincter resting pressure

Laryngoscope Investigative Otolaryngology, 2019
Objective High‐resolution manometry (HRM) is used to analyze upper esophageal sphincter (UES) physiology. Conventional HRM can yield imprecise measurements of UES resting pressure given its unidirectional sensors and averaging of circumferential pressure.
Shun‐ichi Chitose, Yasuro Shin, Kiminori Sato, Sachiyo Hamakawa, Mioko Fukahori, Takeharu Ono, Hirohito Umeno   +6 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Influence of Connecting Two Standalone Mobile Three-Dimensional Scanners on Accuracy Comparing with a Standard Device in Facial Scanning

eJournal of Oral Maxillofacial Research, 2017
Objectives: In this study is investigated if bundling of two scanners leads to better accuracy in recording faces than a standard face-scanning device. Material and Methods: In a group of 28 volunteers, two test specimens were attached to their faces:
Ali Modabber, Florian Peters, Anna Brokmeier, Evgeny Goloborodko, Anna Brokmeier, Alireza Ghassemi, Bernd Lethaus, Frank Hölzle, Stephan Christian Möhlhenrich, Frank Hölzle   +9 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Three-dimensional structure of a low-Reynolds-number turbulent boundary layer [PDF]

, 2004
A low-Reynolds-number zero-pressure-gradient incompressible turbulent boundary layer was investigated using a volumetric imaging technique. The Reynolds number based on momentum thickness was 700.
Delo, C., Smits, A., Kelso, R.
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source