Results 71 to 80 of about 1,177,243 (298)

Soot volume fraction profiling of asymmetric diffusion flames through tomographic imaging [PDF]

, 2014
This paper presents the 3-D (three-dimensional) reconstruction of soot volume fraction of diffusion flames based on tomographic imaging and image processing techniques.
Hossain, Md. Moinul, Lu, Gang, Yan, Yong
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

PEA-CLARITY: Three Dimensional (3D) Molecular Imaging of Whole Plant Organs

Bio-Protocol, 2016
Here we report the adaptation of the CLARITY technique to plant tissues with addition of enzymatic degradation to improve optical clearing and facilitate antibody probe penetration.
William Palmer, Antony Martin, Jamie Flynn, Stephanie Reed, Rosemary White, Robert Furbank, Christopher Grof   +6 more
doaj   +1 more source

Differential Photoelectron Holography: A New Approach for Three-Dimensional Atomic Imaging

, 2003
We propose differential holography as a method to overcome the long-standing forward-scattering problem in photoelectron holography and related techniques for the three-dimensional imaging of atoms.
A. Szöke, B. P. Tonner, B. P. Tonner, C. M. Wei, C. S. Fadley, C. S. Fadley, D. Gabor, D. K. Saldin, D. K. Saldin, D.-A. Luh, E. Rotenberg, H. Wu, J. D. Denlinger, J. J. Barton, J. J. Barton, J. J. Barton, J. Wider, K. Reuter, L. J. Terminello, M. A. Van Hove, M. Tegze, P. Korecki, P. M. Len, P. M. Len, S. D. Kevan, S. G. Bompadre, S. Marchesini, S. Omori, S. Omori, S. Y. Tong, S. Y. Tong, T. Gog, T. Greber, Y. Chen, Y. Nihei   +34 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Three dimensional first-pass myocardial perfusion imaging at 3T: feasibility study

Journal of Cardiovascular Magnetic Resonance, 2008
Background In patients with ischemic heart disease, accurate assessment of the extent of myocardial perfusion deficit may be important in predicting prognosis of clinical cardiac outcomes.
Pohost Gerald M, Hu Houchun H, Shin Taehoon, Nayak Krishna S   +3 more
doaj   +1 more source

Three dimensional rotational angiography imaging of double aortic arch vascular ring [PDF]

, 2013
Three dimensional (3D) rotational angiography is a technique used increasingly for imaging in congenital heart disease. Here the use of this technique for imaging of double aortic arch vascular ring is described and the advantages of this modality. are
Coren, J. S., Coyle, J. C., Ge, Shuping, Mesia, Cesar I., Moulick, Achintya, Patel, Brijesh, Poe, E., Rosenbloom, C., Stevens, R. M., Toib, A.   +9 more
core   +1 more source

Three dimensional optical imaging of blood volume and oxygenation in the neonatal brain [PDF]

, 2006
Optical methods provide a means of monitoring cerebral oxygenation in newborn infants at risk of brain injury. A 32-channel optical imaging system has been developed with the aim of reconstructing three-dimensional images of regional blood volume and ...
Arridge, SR, Austin, T, Branco, G, Delpy, DT, Gibson, AP, Hebden, JC, Meek, JH, Wyatt, JS, Yusof, RM   +8 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Three dimensional scattering center imaging techniques [PDF]

Two methods to image scattering centers in 3-D are presented. The first method uses 2-D images generated from Inverse Synthetic Aperture Radar (ISAR) measurements taken by two vertically offset antennas.
Burnside, W. D., Younger, P. R.
core   +1 more source