Results 61 to 70 of about 1,177,243 (298)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Photon counting compressive depth mapping [PDF]

open access: yes, 2013
We demonstrate a compressed sensing, photon counting lidar system based on the single-pixel camera. Our technique recovers both depth and intensity maps from a single under-sampled set of incoherent, linear projections of a scene of interest at ultra-low
Howell, John C.   +3 more
core   +3 more sources

Three-dimensional imaging of dislocations [PDF]

open access: yesNature, 2013
arising from C.-C. Chen et al. , 74–77 (2013)10.1038/nature12009 At first sight, the achievement of determining atom positions in three dimensions appears spectacular1. Chen and colleagues1 apply a form of tomographic reconstruction to a tilt series of annular dark field (ADF) images of crystalline ...
Peter, Rez, Michael M J, Treacy
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Three-Dimensional Surface Imaging is an Effective Tool for Measuring Breast Volume: A Validation Study

open access: yesArchives of Plastic Surgery, 2016
Background Accurate breast volume assessment is a prerequisite to preoperative planning, as well as intraoperative decision making in breast reconstruction surgery.
Woo Yeon Lee   +4 more
doaj   +1 more source

Proton magnetic resonance imaging with a nitrogen-vacancy spin sensor

open access: yes, 2014
Nuclear magnetic resonance (NMR) imaging with nanometer resolution requires new detection techniques with sensitivity well beyond the capability of conventional inductive detection.
Awschalom, D. D.   +6 more
core   +1 more source

Discrete Imaging Models for Three-Dimensional Optoacoustic Tomography using Radially Symmetric Expansion Functions [PDF]

open access: yes, 2014
Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles.
Er Oraevsky   +5 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Finite-Difference Time-Domain Simulation for Three-dimensional Polarized Light Imaging

open access: yes, 2016
Three-dimensional Polarized Light Imaging (3D-PLI) is a promising technique to reconstruct the nerve fiber architecture of human post-mortem brains from birefringence measurements of histological brain sections with micrometer resolution.
A Taflove   +14 more
core   +1 more source

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