Results 121 to 130 of about 1,882,249 (253)
Series of 4D adult XCAT phantoms for imaging research and dosimetry
, 2020 Computerized phantoms are finding an increasingly important role in medical imaging research. With the ability to simulate various imaging conditions, they offer a practical means with which to quantitatively evaluate and improve imaging devices and ...
E Samei +15 more
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Communications MedicineBackground Nuclear medicine imaging allows for a wide variety of data acquisition and image generation methods in the clinical setting. Imaging phantoms are routinely used to evaluate and optimize image quality and quantitative accuracy of features, but ...
Roberto Fedrigo +7 more
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Hierarchical materials as tissue-like phantoms for photoacoustic imaging
We introduce a hierarchical manufacturing method for creating anatomical phantoms using water-in-elastomer micro-emulsions. This approach addresses the cost, ethical, and technical limitations of animal models, providing a reliable alternative for ...
Daniele Farnesi +25 more
core +1 more source
Application of additive manufacturing for the adaptive design of ultrasound phantoms
Frontiers in PhysicsIntroductionThe image formation process of conventional pulse-echo Ultrasound mainly uses the backscattered amplitude and assumes constant attenuation and speed of sound in the penetrated media.
Lukas Zalka +11 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Design of a UWB wide-slot antenna and a hemispherical array for breast imaging [PDF]
, 2009 A microstrip, fork fed, wide slot antenna, printed on high permittivity substrate has been developed for the transmission of ultra wide bandwidth (UWB) signals into the breast.
Gibbins, David +5 more
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source