Results 91 to 100 of about 53,097 (209)

Outcomes of Kaposi sarcoma in people living with HIV who maintain long‐term viral suppression: A prospective case‐series

HIV Medicine, EarlyView.
Abstract Background Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV‐virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV‐aviraemic KS in a prospective cohort.
S. Bacquart, R. Palich, M. Veyri, S. Bregigeon‐Ronot, M.‐C. Picot, C. Vidal, L. Galicier, S. Choquet, J.‐P. Spano, M.‐A. Valantin, A. Makinson   +10 more
wiley   +1 more source

Cytogenetic Diversity of Variant Philadelphia Translocations in Chronic Myeloid Leukemia

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Chronic myeloid leukemia (CML) is a disease characterized by Philadelphia (Ph) translocations. These translocations can be classical or variant. The structural features and diagnostic implications of variant Philadelphia translocations remain incompletely defined, and they display considerable cytogenetic heterogeneity. Methods In
Ayse Gul Bayrak Tokac, Aynur Aday, Simge Erdem, Gulcin Bagatir, Burak Don, Ozden Ozcan, Akif Selim Yavuz, Sevgi Kalayoglu Besisik, Meliha Nalcaci, Kivanc Cefle, Sukru Ozturk   +10 more
wiley   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Imatinib in the treatment of chronic myeloid leukemia: current perspectives on optimal dose

Blood and Lymphatic Cancer: Targets and Therapy, 2015
Joanna Waclaw,1 Tomasz Sacha,1 Tomasz Stoklosa,21Department of Hematology, Jagiellonian University Collegium Medicum, Kraków, 2Department of Immunology, Medical University of Warsaw, Warsaw, Poland Abstract: Imatinib was the first tyrosine kinase
Waclaw J, Sacha T, Stoklosa T
doaj  

Exceptional therapeutic benefit of imatinib in cKIT‐mutated mucosal melanoma followed by a KIT mutation loss

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Hannah Zillikens, Corinna Scheib, Vicky Peller, Christina Müller, Sebastian Bauer, Ina Pretzell, Klaus Griewank, Antje Sucker, Eva Hadaschik, Felicitas Guntrum, Sven Holger Baum, Alexander Roesch, Selma Ugurel, Dirk Schadendorf, Lisa Zimmer, Elisabeth Livingstone   +15 more
wiley   +1 more source

Salivary Methotrexate as a Predictor of Oral Mucositis in Hematological Cancer Patients: A Phase II Randomized, Double‐Blind Clinical Trial

Oral Diseases, EarlyView.
ABSTRACT Objective To evaluate the efficacy of prophylactic photobiomodulation therapy (PBMT) in preventing oral mucositis (OM) and to assess serum and salivary methotrexate (MTX) levels as predictors of OM in adults receiving high‐dose methotrexate (HD‐MTX).
Letícia Rodrigues‐Oliveira, Carolina Guimarães Bonfim, Ana Leticia Mores, Natalia Rangel Palmier, Henrique Ballassini Abdalla, Juliana Trindade Clemente‐Napimoga, Iara Gonçalves Aquino, Maria Cecilia Querido de Oliveira, Maria Cláudia Cuzzullin, Aljomar Jose Vechiato Filho, Cesar Rivera, Tatiana Natasha Toporcov, Juliana Pereira, Luiz Alcino Gueiros, Rossana Veronica Mendoza López, Manoela Domingues Martins, Marcelo Lazzaron Lamers, Karina Morais‐Faria, Pablo Agustin Vargas, Alan Roger Santos‐Silva, Thais Bianca Brandão, Ana Carolina Prado‐Ribeiro   +21 more
wiley   +1 more source

A Case of Recurrent Pulmonary Tumor Thrombotic Microangiopathy Associated With Gastric Adenocarcinoma Following Imatinib Discontinuation

Pulmonary Circulation
Pulmonary tumor thrombotic microangiopathy (PTTM) is a severe and fatal disease that rapidly causes pulmonary hypertension (PH). While imatinib shows potential for treating PH related to PTTM, it remains unclear if imatinib should continue or be ...
Atsumasa Kurozumi, Shun Minatsuki, Masaru Hatano, Takayuki Tsujimoto, Gota Fujisawa, Satoshi Ishii, Hiroki Yagi, Mai Shimbo, Masako Ikemura, Mitsuhiro Fujishiro, Norihiko Takeda   +10 more
doaj   +1 more source

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson, Kala A. Early, Maritza A. Morales, Klaudia A. Poplawski, Sunetra Das, Dawn L. Duval   +5 more
wiley   +1 more source

Adverse Health Events in Chronic Myeloid Leukaemia Patients Treated With Tyrosine Kinase Inhibitors 2009–2019: A Real‐World Study From the UK's Haematological Malignancy Research Network

International Journal of Cancer, Volume 159, Issue 6, Page 1411-1419, 15 September 2026.
Although tyrosine kinase inhibitors (TKIs) improve chronic myeloid leukemia (CML) outcome, long‐term effects remain unclear, particularly in real‐world settings. Here, the authors examined morbidity and mortality in CML patients treated with TKIs between 2009 and 2019 in the United Kingdom.
Eleanor Kane, Alexandra Smith, Debra Howell, Catherine Cargo, Kate Rothwell, Simone Green, Russell Patmore, Eve Roman   +7 more
wiley   +1 more source

Primary Peritoneal Perivesical Hemangiosarcoma in 16 Dogs (2020–2024)

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Primary peritoneal perivesical hemangiosarcoma in dogs may represent a distinct anatomical presentation of visceral hemangiosarcoma. Despite a high metastatic rate and guarded prognosis, multimodal treatment combining surgery and chemotherapy significantly improved progression‐free and disease‐specific survival compared with chemotherapy alone ...
Jose Roca, Xavier Escoda, Miguel García‐de la Virgen, Ignasi Rodríguez   +3 more
wiley   +1 more source