QSAR-3D/CoMFA em compostos imídicos com atividade antinociceptiva
Imide compounds have shown biological activity. These compounds can be easily synthesized with good yields. The objective of this paper was the rational planning of imides and sulfonamides with antinociceptive activity using the 3D-QSAR/CoMFA approach ...
Maria Elena Walter +2 more
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“Synthesis and Characterization of same Imide Schiff’s bases Derived for Trimethoprim and their biological evaluation” [PDF]
Synthesis and characterization mono imides derivatives for trimethoprim, through reaction of the later with one mole of maleic and phthalic anhydrides, using the classical reflux methods in addition to the microwave technique in the presence of glacial ...
Mohammad F. Mesher +2 more
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Heterogeneous Catalytic Oxidation of Amides to Imides by Manganese Oxides
Herein, we report a one-step peroxide mediated heterogeneous catalytic oxidation of amides to imides utilizing a series of manganese oxides. Among them, Cs/Mn2O3 was found to be the most active catalyst for the selective partial oxidation of N ...
Sourav Biswas +8 more
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Cyclic imide derivatives: As promising scaffold for the synthesis of antimicrobial agents
Cyclic imides as building blocks in the synthesis of natural products, drugs and polymers display a diverse of pharmacological activities such as antibacterial, antifungal, anticonvulsant, anticancer, and anti-inflammatory effects. This review summarizes
Farshid Hassanzadeh, Elham Jafari
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Building lactams by highly selective hydrodeoxygenation of cyclic imides using an alumina-supported AgRe bimetallic nanocatalyst. [PDF]
The rational design of robust nanocatalysts containing the suitable active sites for building relevant organic compounds, such as lactams, is a desired approximation towards the development of a sustainable fine chemistry field. In that sense, the design
Lluna-Galán C +8 more
europepmc +2 more sources
Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides
New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
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Cyclic imides belong to a well-known class of organic compounds with various biological activities, promoting a great interest in compounds with this functional group.
Kariny B. A. Torrent, Elson S. Alvarenga
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Mechanochemical N-alkylation of imides
The mechanochemical N-alkylation of imide derivatives was studied. Reactions under solvent-free conditions in a ball mill gave good yields and could be put in place of the classical solution conditions. The method is general and can be applied to various
Anamarija Briš +2 more
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1-INDANONE DERIVATIVES: A NOVEL ONE-POT APPROACH TO IMIDES VIA BECKMANN-LIKE REARRANGEMENT AND THEORETICAL INSIGHTS INTO THEIR INTERACTIONS WITH ACHE ENZYME [PDF]
The reaction of (E)-2,3-dihydro-1H-inden-1-one oxime (3) with carboxylic acid anhydrides and fatty acids aiming at the formation of the respective esters unexpectedly produced imides [5a-5c and 5d-5k] (81-95% yields).
Thiago R. F. Bastos +4 more
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The preparation of a number of cyclic imide 5-HT1A receptor ligandderivatives has been described. Their structures were conformationally constrained byintroducing rigid linkers containing unsaturated bonds or aromatic benzene rings.
Bożena Kuran +2 more
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