Results 21 to 30 of about 5,947 (295)

Stereoselective Nanocarbon Imides Featuring 12-fold [5]helicenes [PDF]

open access: yes, 2022
Despite the great progress in research on chiral molecular nanocarbons containing multiple helicenes, controlling the stereoselectivity is still a major challenge, especially when attempting to increase the number of helicene moieties.
Yan, Li   +6 more
core   +1 more source

Synthesis and 1,3-Dipolar Cycloaddition Reactions of Chiral Maleimides

open access: yesMolecules, 1997
New routes to the synthesis of various novel chiral maleimides are described. The oxabicyclic anhydride 2 readily available exo-Diels-Alder adduct of furan and maleic anhydride was used as a vehicle, which in turn reacted with hydrochlorides of amino ...
Lubor Fisera, Vladimir Ondrus
doaj   +1 more source

Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders [PDF]

open access: yesFrontiers in Neuroscience, 2021
Neuroinflammation represents a common trait in the pathology and progression of the major psychiatric and neurodegenerative disorders. Neuropsychiatric disorders have emerged as a global crisis, affecting 1 in 4 people, while neurological disorders are the second leading cause of death in the elderly population worldwide (WHO, 2001;GBD 2016 Neurology ...
Yoo Jin Jung   +9 more
openaire   +5 more sources

Mechanochemical N-alkylation of imides

open access: yesBeilstein Journal of Organic Chemistry, 2017
The mechanochemical N-alkylation of imide derivatives was studied. Reactions under solvent-free conditions in a ball mill gave good yields and could be put in place of the classical solution conditions. The method is general and can be applied to various
Anamarija Briš   +2 more
doaj   +1 more source

1-INDANONE DERIVATIVES: A NOVEL ONE-POT APPROACH TO IMIDES VIA BECKMANN-LIKE REARRANGEMENT AND THEORETICAL INSIGHTS INTO THEIR INTERACTIONS WITH ACHE ENZYME [PDF]

open access: yesQuímica Nova
The reaction of (E)-2,3-dihydro-1H-inden-1-one oxime (3) with carboxylic acid anhydrides and fatty acids aiming at the formation of the respective esters unexpectedly produced imides [5a-5c and 5d-5k] (81-95% yields).
Thiago R. F. Bastos   +4 more
doaj   +1 more source

Synthesis and Identification of Epoxy Derivatives of 5-Methylhexahydroisoindole-1,3-dione and Biological Evaluation

open access: yesMolecules, 2021
Cyclic imides belong to a well-known class of organic compounds with various biological activities, promoting a great interest in compounds with this functional group.
Kariny B. A. Torrent, Elson S. Alvarenga
doaj   +1 more source

The preparation of N-alkyl acyclic imides

open access: yes, 1996
An optimized method for the preparation of a little known class of compounds, acyclic imides, is described. First, the N-metalation of selected secondary am des was examined, using various bases and solvents. The most efficient metalating agent was found
Lečić, V.M.   +5 more
core   +4 more sources

Synthesis of Conformationally Constrained Aryl- or Heteroarylpiperazinyl Derivatives of Selected Imides as 5-HT1A Receptor Ligands

open access: yesMolecules, 2006
The preparation of a number of cyclic imide 5-HT1A receptor ligandderivatives has been described. Their structures were conformationally constrained byintroducing rigid linkers containing unsaturated bonds or aromatic benzene rings.
Bożena Kuran   +2 more
doaj   +1 more source

Titanium- and Lewis Acid-Mediated Cyclopropanation of Imides

open access: yes, 2016
We report a straightforward synthesis of 1-azaspirocyclopropane lactams from imides. Following the described procedure, polycyclic nitrogen heterocycles containing a cyclopropane unit could be obtained from unsaturated ...
Jan Szymoniak (1939225)   +1 more
core   +1 more source

Hydroarylation reactions of N-acylaminosubstituted tricyclic imides

open access: yes, 2013
The palladium-catalysed hydroarylation of unsaturated N-acylamino-substituted tricyclic imides provided a new stereoselective synthesis of exo-aryl(heteroaryl)-substituted tricyclic N-acylamino ...
Gul, Melek, Kulu, Irem, Ocal, Nuket
core   +1 more source

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