Results 101 to 110 of about 539,131 (366)

Homologous expression and purification of human HAX‐1 for structural studies

open access: yesFEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Young Children Selectively Imitate Models Conforming to Social Norms

open access: yesFrontiers in Psychology, 2019
This study investigated whether toddlers would selectively imitate a demonstrator who exhibits familiarity with cultural practices in their tool-using habits over a demonstrator who consistently uses tools in an unconventional way.
Katalin Oláh   +3 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Ouverture de ‘Global Networks and Local Development-1’

open access: yesSymphonya, 2013
The global competitive landscapes of innovation and imitation have significantly changed the relative position of many Nation-States and the business relations between global networks and local firms. The US large corporations have lost their historical
Silvio M. Brondoni
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

How Much of Language Acquisition Does Operant Conditioning Explain?

open access: yesFrontiers in Psychology, 2017
Since the 1950s, when Chomsky argued that Skinner’s arguments could not explain syntactic acquisition, psychologists have generally avoided explicitly invoking operant or instrumental conditioning as a learning mechanism for language among human children.
Christopher B. Sturdy, Elena Nicoladis
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Spiel nach Gehör auf der Violine – Wie beeinflusst musikalische Vorerfahrung die Imitation kulturell vertrauter und fremder Melodiemuster?

open access: yesJahrbuch Musikpsychologie, 2019
Spiel nach Gehör ist eine wesentliche, doch vielfach vernachlässigte musikalische Grundfertigkeit. Nach dem Modell mentaler Repräsentationen musikalischer Performanz basiert Spiel nach Gehör auf der Klangvorstellung (goal imaging) und der ...
Anja-Maria Hakim, Claudia Bullerjahn
doaj   +1 more source

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