Results 81 to 90 of about 36,564 (266)

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Young Children Selectively Imitate Models Conforming to Social Norms

open access: yesFrontiers in Psychology, 2019
This study investigated whether toddlers would selectively imitate a demonstrator who exhibits familiarity with cultural practices in their tool-using habits over a demonstrator who consistently uses tools in an unconventional way.
Katalin Oláh   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Cognitive map plasticity and imitation strategies to improve individual and social behaviors of autonomous agents

open access: yesPaladyn, 2010
Starting from neurobiological hypotheses on the existence of place cells (PC) in the brain, the aim of this article is to show how little assumptions at both individual and social levels can lead to the emergence of non-trivial global behaviors in a ...
Laroque Philippe   +4 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Ouverture de ‘Global Networks and Local Development-1’

open access: yesSymphonya, 2013
The global competitive landscapes of innovation and imitation have significantly changed the relative position of many Nation-States and the business relations between global networks and local firms. The US large corporations have lost their historical
Silvio M. Brondoni
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

How Much of Language Acquisition Does Operant Conditioning Explain?

open access: yesFrontiers in Psychology, 2017
Since the 1950s, when Chomsky argued that Skinner’s arguments could not explain syntactic acquisition, psychologists have generally avoided explicitly invoking operant or instrumental conditioning as a learning mechanism for language among human children.
Christopher B. Sturdy, Elena Nicoladis
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Imitation Primer

open access: yes, 2020
In this Primer, Cecilia Heyes explains why imitation is thought to be a mark of cognitive complexity and an inheritance mechanism for cumulative culture. Recent research involving birds, ‘enculturated’ chimpanzees, and humans suggests that the cognitive mechanisms that make imitation possible are constructed during development through social ...
openaire   +3 more sources

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