Results 51 to 60 of about 661,741 (245)

A Case of Immediate Hypersensitivity Reaction to Maltitol

Case Reports in Medicine, 2017
Background. Maltitol is a sugar alcohol that is frequently used as a noncaloric sweetener, although it is also used as an excipient, a plasticizer in gelatin capsules, and an emollient.
Ana Rodríguez Trabado, Carmen Cámara Hijón, José Antonio García-Trujillo, Irene Magriz Trascón, Luis Miguel Fernández Pereira   +4 more
doaj   +1 more source

The Time Delay Between Drug Intake and Bronchospasm for Nonsteroidal Antiinflammatory Drugs Sensitive Patients

World Allergy Organization Journal, 2010
A study was performed to assess the time between drug intake and drug induced hypersensitivity reaction for patients sensitive to nonsteroidal antiinflammatory drugs (NSAID) in clinical patient history and after oral provocation tests.
Giedre Grigiene, MD, Jolita Norkūnienė, PhD, Violeta Kvedariene, MD, PhD   +2 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions

Clinics, 2018
OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine ...
Laila S. Garro, Marcelo V. Aun, Iracy Sílvia C. Soares, Marisa R. Ribeiro, Antônio A. Motta, Jorge Kalil, Mariana C. Castells, Maria José C. Carmona, Pedro Giavina-Bianchi   +8 more
doaj   +1 more source

Hypersensitivity to Gadolinium-Based Contrast Media

Frontiers in Allergy, 2022
Gadolinium-based contrast agents (GBCAs) are frequently used in magnetic resonance imaging (MRI) examinations to increase sensitivity in diagnoses. Recently, an increase in the description of hypersensitivity reactions to GBCAs has been detected.
M. Teresa Gracia Bara, M. Teresa Gracia Bara, Alicia Gallardo-Higueras, Esther M. Moreno, Esther M. Moreno, Esther M. Moreno, Esther M. Moreno, Elena Laffond, Elena Laffond, Elena Laffond, Francisco J. Muñoz Bellido, Francisco J. Muñoz Bellido, Francisco J. Muñoz Bellido, Cristina Martin, Cristina Martin, Miriam Sobrino, Miriam Sobrino, Eva Macias, Eva Macias, Eva Macias, Sonia Arriba-Méndez, Sonia Arriba-Méndez, Sonia Arriba-Méndez, Rosita Castillo, Ignacio Davila, Ignacio Davila, Ignacio Davila, Ignacio Davila   +27 more
doaj   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

Acute coronary syndrome in diclofenac sodium-induced type I hypersensitivity reaction : Kounis syndrome [PDF]

, 2007
Drug-induced type I hypersensitivity reactions are frequent. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction.
Panic, Milos, Putnikovic, Biljana, Jankovic-Gavrilovic, Jelena, Rasic-Milutinovic, Zorica, Gluvic, Zoran M., Stojkovic, Aleksandra   +5 more
core  

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

HLA-B*5701 screening for hypersensitivity to Abacavir [PDF]

, 2008
Background Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele. This study was designed to establish the effectiveness of prospective HLA-B*5701 screening to prevent the hypersensitivity reaction to ...
Jagel-Guedes, E., Kozyrev, O., Phillips, E., Fitch, N., Thorborn, D., Molina, J-M, Hughes, A., Cid, J.F., Rugina, S., Nolan, D., Carosi, G., Hay, P., Ryan, S., Tomazic, J., Hughes, S., Benbow, A., Mallal, S., Workman, C.   +17 more
core  

Case series of sebelipase alfa hypersensitivity reactions and successful sebelipase alfa rapid desensitization

JIMD Reports, 2019
Allergic immune‐mediated hypersensitivity reactions are known potential complications of enzyme replacement therapy. Sebelipase alfa, recombinant lysosomal acid lipase (LAL), is a potentially life‐altering treatment for patients with LAL deficiency ...
Michelle F. Huffaker, Anne Y. Liu, Gregory M. Enns, Suresh Vijay, Antonio J. Amor, N. Franklin Adkinson Jr   +5 more
doaj   +1 more source