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Oxidative stress and haematological changes in immobilized rats

Acta Physiologica Scandinavica, 1999
Immobilization stress induces formation of reactive oxygen species (ROS) and leads to the oxidative injury in various tissues. In this study, the effects of immobilization stress on peripheral blood cells distribution, plasma level of thiobarbituric acid reactive substances (TBARS), and activities of antioxidant enzymes in erythrocytes were ...
K, Oishi   +7 more
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Reaction of rat brain capillaries to immobilization stress

Neuroscience and Behavioral Physiology, 2008
The calcium adenosine triphosphate method of Chilingaryan was used to study the morphofunctional state of the capillary component of the microcirculatory bed of the brain in rats at different time points after experimental immobilization stress (fixation of the animal on its back for 2 h).
openaire   +2 more sources

Pituitary-Thyroid Function during Acute Immobilization Stress in Rats

Experimental and Clinical Endocrinology & Diabetes, 2009
In nine experiments a total of 394 male Wistar rats weighing about 300 g was used. In each experiment, one intact control group was used and several other groups were subjected to immobilization (IMO) for 2 to 240 min in a prone position by inserting their heads through steel wire loops fixed on a board and by fasting their limbs to four metal strips ...
P, Langer   +5 more
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Immobilization Stress and Direct Glucocorticoid Effects on Rat Septohippocampus

International Journal of Neuroscience, 1988
The rat septohippocampal cholinergic system to a large extent regulates the adaptive physiological and behavioral response to stress. The mesoseptal dopaminergic (DA) system, one of the converging inputs to the lateral septum, exerts a tonic inhibitory action on the septohippocampal cholinergic neurons.
Y, Finkelstein   +4 more
openaire   +2 more sources

Effect of chronic nicotine treatment against repeated immobilization stress

Pharmacology Biochemistry and Behavior, 1987
Alpha 2 and beta adrenoceptors, and muscarinic cholinoceptors in 2 brain regions (cerebral cortex and hippocampus) were measured in rats which received either tap water or nicotine added to the drinking water (5-8 mg/kg/day) for 4 weeks, and immobilization stress (daily 2 hr) for the last 5 days.
K, Yamanaka, I, Muramatsu, S, Kigoshi
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Immobilization stress-induced anorexia is mediated independent of MyD88

NeuroReport, 2016
MyD88 is an adaptor protein for the toll-like receptor, which is involved in regulating innate immune function. Lipopolysaccharide-induced activation of toll-like receptor 4 signaling induces hypothalamic signal transducer and activator of transcription 3 (STAT3) phosphorylation and anorexia through MyD88.
Toru, Hosoi   +3 more
openaire   +2 more sources

Immobilization stress induces XBP1 splicing in the mouse brain

Biochemical and Biophysical Research Communications, 2019
Cells activate the unfolded protein response (UPR) to cope with endoplasmic reticulum (ER) stress. In the present study, we investigated the possible involvement of psychological stress on UPR induction in the mouse brain. When mice were exposed to immobilization stress for 8 h, XBP1 mRNA splicing was significantly induced in the hippocampus, cortex ...
Toru Hosoi   +4 more
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Neuropeptide Y and leptin receptor expression in the hypothalamus of rats with chronic immobilization stress

Neural Regeneration Research, 2013
In this study, Sprague-Dawley rats were immobilized to a frame for 3 hours a day for 21 days to establish a model of chronic immobilization stress. The body weight and food intake of rats subjected to chronic immobilization stress were significantly ...
Shao-xian Wang   +5 more
semanticscholar   +1 more source

Hesperidin May Protect Gastric Tissue against Immobilization Stress

2021
OBJECTIVE: To investigate antioxidant properties of hesperidin against gastric lesions in immobilized rats with immunostaining of caspase-3 and IL-10. STUDY DESIGN: Thirty male Wistar albino rats were assigned to control, stress, and stress+ hesperidin groups.
Beskisiz, Songül, Aşır, Fırat
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Immobilization Stress Increases Hepatic IL-6 Expression in Mice

Biochemical and Biophysical Research Communications, 1997
When mice were subjected to restriction of movement in a small cylinder (immobilization stress), the serum interleukin (IL)-6 level rose in 1 h, following increased expression of IL-6 mRNA in both the liver and the spleen. The IL-6 mRNA induction was much greater in the liver than in the spleen when compared on a whole-organ basis.
H, Kitamura   +5 more
openaire   +2 more sources

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