Results 251 to 260 of about 2,310,619 (425)

Continuous production of maltose using a dual immobilized enzyme system.

open access: bronze, 1989
Masahiro Yoshida   +4 more
openalex   +2 more sources

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai   +12 more
wiley   +1 more source

Comparative study for enzymatic hydrolysis of sugarcane bagasse using free and nanoparticle immobilized holocellulolytic enzyme cocktail

open access: yesWaste Management Bulletin
This study aimed at a comparative analysis of enzymatic hydrolysis of sugarcane bagasse biomass by using a free holocellulase cocktail of an enzyme (Cellic CTec2) and immobilized enzyme system on IOMNP@SiO2-NH2 support to make the process cost-effective.
Arti Yadav   +5 more
doaj  

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

Magnetite Nanoparticles with High Affinity Toward Target Protein for Efficient and Facile Bio‐Separation

open access: yesAdvanced Science, EarlyView.
BSA‐imprinted magnetite nanoparticles with high adsorption capacity, high selectivity, fast adsorption kinetics, and high magnetic susceptibility are synthesized using surface enzyme‐mediated polymerization and polyglutamic acid‐based peptide crosslinker.
Yafei Wang   +8 more
wiley   +1 more source

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

open access: yesAdvanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li   +11 more
wiley   +1 more source

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