Results 111 to 120 of about 11,576 (268)
Bioethics, EarlyView.ABSTRACT At its core, transhumanism is utopic and apocalyptic: it tells us we will be saved through an imminent radical change of our being wrought by radical human enhancement (RHE) technologies. We are rushing, its supporters claim, towards a technological utopia so long as assorted techno‐phobes do not stand in the way.
Benjamin N. Parks
wiley +1 more source
Hledání duše v Británii v první polovině 19. století. Diskurz teologie, vědy a kultury [PDF]
Historie - Otázky - ProblémyThis paper explores the discourse concerning the nature of the human soul in Britain during the first half of the 19th century. It focuses on the religious, philosophical and scientific concepts of the human soul and its (im)mortality within the context ...
Marie Michlová
doaj
British Journal of Haematology, EarlyView.Summary Diffuse large B‐cell lymphoma (DLBCL) is the most common aggressive non‐Hodgkin lymphoma and is characterized by substantial heterogeneity. This study aimed to develop a liquid–liquid phase separation (LLPS)‐related prognostic model to improve risk stratification.
Zhen‐Zhong Zhou +11 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Secondary central nervous system lymphoma (SCNSL) remains a rare but challenging manifestation of aggressive lymphomas, with limited prospective data to guide treatment decisions in the modern therapeutic era. We conducted a multicentre retrospective cohort study of 105 consecutively treated adult patients diagnosed with SCNSL between 2016 and ...
Farina Eigendorff +10 more
wiley +1 more source
Intermediate clinical endpoints as surrogates for overall survival after salvage prostatectomy
BJU International, EarlyView.Objectives To evaluate biochemical recurrence‐free survival (BRFS) and metastasis‐free survival (MFS) as potential intermediate clinical endpoints (ICEs) for overall survival (OS) in patients undergoing salvage radical prostatectomy (sRP). Patients and Methods Evaluable patients were selected from a retrospective dataset, resulting in a cohort of 879 ...
Navid Roessler +22 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn +11 more
wiley +1 more source
Children &Society, EarlyView.Abstract This article explores the ways in which ‘forest school’, an educational approach where children engage in creative and play based activities in a ‘natural’ environment, can contribute towards Sustainable Development Goal 15 (SDG 15) by promoting sustainable use of terrestrial ecosystems and by helping address biodiversity loss. Drawing on data
Hannah Hogarth
wiley +1 more source
Children &Society, EarlyView.ABSTRACT Modern deaths have become reiterations. That is, despite exhibiting a seemingly high‐level of diversity in death's representations in everyday lives, death suffers from a particular onto‐epistemological poverty that prevents it from being imagined otherwise.
Zhaoxi Zheng +2 more
wiley +1 more source
‘Do You Realise People Are Dying There?!’: Ukrainian Adolescents Reflecting on Death During Wartime
Children &Society, EarlyView.ABSTRACT This article explores how Ukrainian refugee adolescents in Romania think and speak about death and loss amid war and displacement. While contemporary Western societies display an unprecedented visibility of death, they continue to exclude children from genuine conversations about mortality, maintaining a protective silence.
Adriana Teodorescu, Alina Bărbuță
wiley +1 more source