Results 121 to 130 of about 16,577 (248)
SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting
Medicinal Research Reviews, EarlyView.ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama +2 more
wiley +1 more source
Statin Exposure and Survival Outcomes in Amyotrophic Lateral Sclerosis in an Asian Cohort
Muscle &Nerve, EarlyView.ABSTRACT Introduction Data from Asian cohorts on whether statin therapy affects amyotrophic lateral sclerosis (ALS) progression are limited. We examined whether statin exposure was associated with ALS disease duration or tracheostomy‐free survival in a multiethnic Asian ALS cohort.
Anushika Raheja +5 more
wiley +1 more source
Immortality in view of Maimonides and Spinoza
Journal of Philosophical Investigations, 2014 Desire for immortality can be seen as the essential natural impulse. Therefore, different religions and thinkers have attempted to see the issue from different viewpoints. The great Jewish philosopher.
Morteza Shajari +2 more
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Towards greener yttrium‐catalyzed ring‐opening polymerization via an all‐terpene reaction concept
Polymer International, EarlyView.Development of a terpene‐based catalytic system for ring‐opening polymerization of bio‐based lactones that reveals the steric effects of the nucleophile on initiation and alkoxide exchange, while simultaneously enabling post‐polymerization functionalization.
Lea‐Sophie Hornberger +3 more
wiley +1 more source
PROTEOMICS, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) represents the most aggressive subtype with limited therapeutic options and the poorest clinical outcomes. Using high‐resolution nUPLC‐QTOF‐MS/MS, we performed comprehensive proteomic profiling of TNBC cell lines representing disease progression stages: HCC‐1937 (stage IIB), HCC‐1599 (stage IIIA), and MDA ...
Claudia Sissely Chaviano‐Montes de Oca +7 more
wiley +1 more source
Hledání duše v Británii v první polovině 19. století. Diskurz teologie, vědy a kultury [PDF]
Historie - Otázky - ProblémyThis paper explores the discourse concerning the nature of the human soul in Britain during the first half of the 19th century. It focuses on the religious, philosophical and scientific concepts of the human soul and its (im)mortality within the context ...
Marie Michlová
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, 1910 William Jennings Bryan talks about immortality and gives examples of resurrection in plant and animal life, giving proof that there is a life ...
Bryan, William Jennings, 1860-1925
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Recompensation of Cirrhosis: A New Treatment‐Related Disease State
Portal Hypertension &Cirrhosis, EarlyView.This perspective article conceptualizes recompensation of cirrhosis as a distinct treatment‐related disease state rather than mere transient clinical improvement after etiology‐directed therapy, and further proposes a four‐state classification including compensated cirrhosis, stable recompensation, unstable recompensation, and persistent decompensation
Wentao Tan +5 more
wiley +1 more source
The "digital death" phase: technological discourse and the contemporary imaginary
Семиотические исследованияThe article examines the transformation of the phenomenon of death in the first quarter of the 21st century, marked by a shift from the "spectacular" to the "digital" phase.
Daria S. Bylieva
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