Results 141 to 150 of about 11,576 (268)

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti   +11 more
wiley   +1 more source

Delusions of Immortality in a Post-War Society: The Albanian Case

open access: yesFrontiers in Psychiatry, 2019
Gentian Vyshka, Ariel Çomo
doaj   +1 more source

Target Trial Emulation in Observational Research—Strengths, Limitations, and Methodological Considerations

open access: yesJournal of Periodontal Research, EarlyView.
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister   +6 more
wiley   +1 more source

Study Design in Clinical and Epidemiologic Research: Observational, Experimental, and Beyond

open access: yesJournal of Periodontal Research, EarlyView.
Population‐based epidemiology and clinical research are complementary and mutually reinforcing: Epidemiology quantifies disease incidence/prevalence and elucidates environmental and social determinants in populations, whereas clinical research evaluates biomarkers, therapeutics, and prognostic outcomes in patients; their convergence underpins ...
Gustavo G. Nascimento   +3 more
wiley   +1 more source

Guises of Despair

open access: yes
European Journal of Philosophy, EarlyView.
Béatrice Han‐Pile
wiley   +1 more source

Cohort and Case–Control Studies: Strengths, Limitations and Methodological Considerations

open access: yesJournal of Periodontal Research, EarlyView.
Population‐based epidemiology and clinical research are complementary by design—and nowhere is that more evident than in cohort studies. By following individuals over time, cohorts quantify disease incidence, elucidate environmental and social determinants and evaluate biomarkers and prognostic outcomes within a single longitudinal framework.
Nasir Z. Bashir   +4 more
wiley   +1 more source

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