Results 191 to 200 of about 5,479,910 (356)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age-Related Diseases. [PDF]

Immunol Rev
Richter L, Dias-Ferreira J, Campos Ramos G, Ashour D.   +3 more
europepmc   +1 more source

Additional file 2 of A comprehensive dynamic immune acetylproteomics profiling induced by Puccinia polysora in maize

, 2023
Jianfei Guo, Zhigang Ma, Ce Deng, Junqiang Ding, Yuxiao Chang   +4 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Immune Checkpoint Inhibitor-Associated Hepatobiliary Toxicity: A Case of Concurrent Immune-Mediated Hepatitis and Acalculous Cholecystitis. [PDF]

ACG Case Rep J
Ravella B, Gadde EC, Lokineni S.
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

A Case of Fulminant Immune-Related Enterocolitis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Carcinoma. [PDF]

IJU Case Rep
Kanai K, Sumiyoshi T, Kitamoto H, Teramoto Y, Mine Y, Kono J, Masui K, Goto T, Saito R, Kobayashi T.   +9 more
europepmc   +1 more source

An epithelial-mesenchymal transition-related long non-coding RNA signature to predict overall survival and immune microenvironment in kidney renal clear cell carcinoma

, 2021
Youpeng Zhang, Yongbiao Cheng, Sen Li, Ning Zhao, Zhaohui Zhu   +4 more
openalex   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

CD39/CD73-mediated immunosuppression and tumor aggressiveness in bladder cancer. [PDF]

Cancer Immunol Immunother
Furriel F, Laranjeira P, Pereira M, Silva S, Silva I, Fontinha G, Sousa V, Gomes C, Parada B, Paiva A.   +9 more
europepmc   +1 more source