Results 141 to 150 of about 14,522,121 (350)

In Vivo Chronic Stimulation Unveils Autoreactive Potential of Wiskott–Aldrich Syndrome Protein-Deficient B Cells

Frontiers in Immunology, 2017
Wiskott–Aldrich syndrome (WAS) is a primary immunodeficiency caused by mutations in the gene encoding the hematopoietic-specific WAS protein (WASp). WAS is frequently associated with autoimmunity, indicating a critical role of WASp in maintenance of ...
Anna Villa, Anna Villa, Marita Bosticardo, Maria Carmina Castiello, Francesca Pala, Lucia Sereni, Lucia Sereni, Elena Draghici, Donato Inverso, Aisha V. Sauer, Francesca Schena, Elena Fontana, Enrico Radaelli, Paolo Uva, Karla E. Cervantes-Luevano, Federica Benvenuti, Pietro L. Poliani, Matteo Iannacone, Matteo Iannacone, Matteo Iannacone, Elisabetta Traggiai   +20 more
doaj   +1 more source

Immunotherapy Based on Dendritic Cell-Targeted/-Derived Extracellular Vesicles—A Novel Strategy for Enhancement of the Anti-tumor Immune Response [PDF]

, 2019
Oleg V. Markov, Anastasiya Oshchepkova, Н. Л. Миронова   +2 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Regulation of Ovarian Cancer Prognosis by Immune Cells in the Tumor Microenvironment [PDF]

, 2018
Maureen L. Drakes, Patrick J. Stiff
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers [PDF]

, 2018
Daniel J. McGrail, Lorenzo Federico, Yongsheng Li, Hui Dai, Yiling Lu, Gordon B. Mills, S. Stephen Yi, Shiaw-Yih Lin, Nidhi Sahni   +8 more
openalex   +1 more source

Immune Infiltrates of m6A RNA Methylation-Related lncRNAs and Identification of PD-L1 in Patients With Primary Head and Neck Squamous Cell Carcinoma

, 2021
Ziyi Feng, Haoyu Gao, Tianda Feng
openalex   +1 more source

Expression of MHC II genes

, 2005
Innate and adaptive immunity are connected via antigen processing and presentation (APP), which results in the presentation of antigenic peptides to T cells in the complex with the major histocompatibility (MHC) determinants.
Drozina, G., Jabrane-Ferrat, N., Kohoutek, J., Peterlin, B. M.   +3 more
core   +2 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Exosomes Derived from Immune Cells: The New Role of Tumor Immune Microenvironment and Tumor Therapy

International Journal of Nanomedicine, 2022
Shiyang Wang, Yue Shi Department of Geriatric Surgery, The First Hospital of China Medical University, Shenyang, 110001, People’s Republic of ChinaCorrespondence: Yue Shi, Department of Geriatric Surgery, The First Hospital of China Medical ...
Wang S, Shi Y
doaj