Results 171 to 180 of about 3,195,227 (346)
Immune Factors, Immune Cells and Inflammatory Diseases
The immune system comprises distinct innate and adaptive arms, each of which contains many layers to provide a coordinated, sequential immune response to insults [...]
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Sex in Immune Cells and Parasitic Diseases - A Complex Relationship. [PDF]
Honecker B, Hansen CS, Lotter H.
europepmc +1 more source
Reflections on immune checkpoint inhibition in non-small cell lung cancer.
Konstantinos Leventakos +1 more
openalex +1 more source
P060 Immune unresponsiveness of human intestinal dendritic cells in ulcerative colitis is reversed by a novel bacterial peptide STp [PDF]
Hafid O. Al‐Hassi +9 more
openalex +1 more source
Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga +2 more
wiley +1 more source

