Results 231 to 240 of about 3,195,227 (346)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Ferroptosis of Immune Cells in Infection, Inflammation and Tumor Progression. [PDF]

Biomolecules
Xu H, Lu Y, Zeng Q, Zhu X, Guan W, Liu S.   +5 more
europepmc   +1 more source

Single-cell immune profiling and validation of PBMCs in the onset of and recovery from herpes zoster [PDF]

Longsheng Xu, Shang Zheng, Shuyao Zhang, Xiang‐Yao Li, Yong Fei, Lei Yang, beibei Liu, Kangli Shen, Qinli Feng, Qinghe Zhou, Ming Yao   +10 more
openalex   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A Mortise of Immune Cells: Leprosy with Disseminated Dermatophytosis. [PDF]

J Glob Infect Dis
Singh S, Upadhyaya A, Islahi S, Gupta S.
europepmc   +1 more source

Sea urchin immune cells and associated microbiota co-exposed to iron oxide nanoparticles activate cellular and molecular reprogramming that promotes physiological adaptation

Andi Alijagić, Roberta Russo, Viviana Scuderi, Martina Ussia, Silvia Scalese, Simona Taverna, Magnus Engwall, Annalisa Pinsino   +7 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

NETosis and pyroptosis of immune cells in sepsis. [PDF]

J Transl Int Med
Kashif AM, Ouyang Y, Li Y, Pan B.
europepmc   +1 more source

Insulitis and aging: Immune cell dynamics in Langerhans islets

Julia Jelleschitz, Sophie Heider, Richard Kehm, Peter Baumgarten, Christiane Ott, Vanessa Schnell, Tilman Grune, Annika Höhn   +7 more
openalex   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source