Results 261 to 270 of about 2,266,569 (385)

The effect of common medications on the efficacy of immune checkpoint inhibitors. [PDF]

Cancer
Brinzevich D, Falvello V, Rehmani SS, Strohbehn GW, Ramnath N, Dykstra MP, Higgins LM, Elliott D, Schipper MJ, Green MD, Bryant AK.   +10 more
europepmc   +1 more source

Table 1_Tumor-suppressing multi-enterobacteria and PD-1/PD-L1 immune checkpoint inhibitor combination improves the outcome of hepatocellular carcinoma therapy.xls

Dongjuan Wu (11578597), Yaohua Fan (7865972), Mingsheng Zhang (122627), Xiaoguang Wang (425047), Xuesong He (292081), Xinwei Guo (4668970), Yangchen Liu (732758), Chenxi Cao (5646899), Zhaoqun Deng (91450)   +8 more
openalex   +1 more source

Radiotherapy, tyrosine kinase inhibitors, immune checkpoint inhibitors combined with hepatic arterial infusion chemotherapy of RALOX versus FOLFOX for hepatocellular carcinoma with portal vein tumor thrombus: a propensity score-matching cohort study [PDF]

Hao-Yang Tan, Shuangquan Liu, Yanhan Liu, Guohua Dai, Jiu-Ling Zheng, Hua-Guo Feng   +5 more
openalex   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Guillain-Barré syndrome associated with immune checkpoint inhibitors exposure: a pharmacovigilance study. [PDF]

J Neurol
Cabon J, Ducloie M, Chretien B, Arnaud C, Alexandre J, Dolladille C, Da Silva A.   +6 more
europepmc   +1 more source

Table 2_HDAC6 inhibition by ITF3756 modulates PD-L1 expression and monocyte phenotype: insights for a promising immune checkpoint blockade co-treatment therapy.xlsx

Valeria Spadotto (12491785), Chiara Ripamonti (7971695), Andrea Ghiroldi (470525), Elisabetta Galbiati (1618450), Pietro Pozzi (7971722), Roberta Noberini (192067), Tiziana Bonaldi (35979), Christian Steinkühler (2699590), Gianluca Fossati (5542202)   +8 more
openalex   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Editorial: Immune-checkpoint inhibitors and immunometabolic reprogramming in cancer immunotherapy. [PDF]

Front Immunol
Kumar V, De Falco V.
europepmc   +1 more source

Myocarditis in Patients Treated With Immune Checkpoint Inhibitors.

Journal of the American College of Cardiology, 2018
Syed S Mahmood, M. Fradley, J. Cohen, A. Nohria, K. Reynolds, L. Heinzerling, R. Sullivan, Rongras Damrongwatanasuk, Carol L Chen, Dipti Gupta, M. Kirchberger, Magid Awadalla, Malek Z O Hassan, J. Moslehi, Sachin P. Shah, S. Ganatra, P. Thavendiranathan, D. Lawrence, J. Groarke, T. Neilan   +19 more
semanticscholar   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source