Results 191 to 200 of about 268,746 (338)

Additional file 1: of Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors

, 2019
Jeffrey M. Conroy, Sarabjot Pabla, Mary Nesline, Sean T. Glenn, Antonios Papanicolau‐Sengos, Blake Burgher, Jonathan Andreas, Vincent Giamo, Yirong Wang, Felicia L. Lenzo, Wiam Bshara, Maya Khalil, Grace K. Dy, Katherine Madden, Keisuke Shirai, Konstantin H. Dragnev, Laura J. Tafe, Jason Zhu, Matthew Labriola, Daniele Marin, Shannon J. McCall, Jeffrey Clarke, Daniel J. George, Tian Zhang, Matthew R. Zibelman, Pooja Ghatalia, Isabel Araujo-Fernandez, Luis de la Cruz‐Merino, Arun K. Singavi, Ben George, Alexander C. Mackinnon, Jonathan R. Thompson, Rajbir Singh, Robin Jacob, Deepa Kasuganti, Neel Shah, Roger Day, Lorenzo Galluzzi, Mark Gardner, Carl Morrison   +39 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

The effect of common medications on the efficacy of immune checkpoint inhibitors. [PDF]

Cancer
Brinzevich D, Falvello V, Rehmani SS, Strohbehn GW, Ramnath N, Dykstra MP, Higgins LM, Elliott D, Schipper MJ, Green MD, Bryant AK.   +10 more
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Guillain-Barré syndrome associated with immune checkpoint inhibitors exposure: a pharmacovigilance study. [PDF]

J Neurol
Cabon J, Ducloie M, Chretien B, Arnaud C, Alexandre J, Dolladille C, Da Silva A.   +6 more
europepmc   +1 more source

Baseline geriatric 8 (G8) screening tool predicts overall survival in metastatic urothelial carcinoma treated with immune checkpoint inhibitors

Christopher H. Rhee, Subir Goyal, Y. Liu, Dylan J. Martini, Julie M. Shabto, Bassel Nazha, Omer Kucuk, Bradley Curtis Carthon, Mehmet Asim Bilen, Jacqueline T. Brown   +9 more
openalex   +1 more source

Effect of Liver Metastases on Survival in Microsatellite-Stable Metastatic Colorectal Cancer Treated with Immune Checkpoint Inhibitors [PDF]

Nussara Pakvisal, Leontios Pappas, Bennett Adam Caughey, Kuldeep Kumar, Noelia Tarazona, Kruti B. Vora, Ben Ouyang, Aditya Pandey, Bryan L. Peacker, Joie Sun, Leyre Zubiri, Kerry L. Reynolds, Ryan Dp, Motaz Qadan, Ryan B. Corcoran, Bruce Giantonio, Jill N. Allen, Elizabeth P. Walsh, Jefferey W. Clark, David Ting, Aparna R. Parikh   +20 more
openalex   +1 more source

Generalizability of immune checkpoint inhibitor trials to real-world patients with advanced non-small cell lung cancer

, 2022
Mónica Tang, Chee Khoon Lee, Craig Lewis, Michael Boyer, Bernadette Brown, Andrea L. Schaffer, Sallie‐Anne Pearson, R. J. Simes   +7 more
openalex   +2 more sources

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

Advanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen, Zichen Liu, Mengyi Wei, Qian Li, Liang Wu, Kunyuan Yu, Yanhong Xu, Dainan Yu, Wenwu Ma, Hongmei Wang, Ng Shyh‐Chang, Jinglei Zhai   +11 more
wiley   +1 more source

Editorial: Immune-checkpoint inhibitors and immunometabolic reprogramming in cancer immunotherapy. [PDF]

Front Immunol
Kumar V, De Falco V.
europepmc   +1 more source