Results 141 to 150 of about 1,940,572 (373)

Alum Activates the Bovine NLRP3 Inflammasome

Frontiers in Immunology, 2017
There has been a move away from vaccines composed of whole or inactivated antigens toward subunit-based vaccines, which although safe, provide less immunological protection.
Ciaran Harte, Ciaran Harte, Aoife L. Gorman, S. McCluskey, Michael Carty, Andrew G. Bowie, C. J. Scott, Kieran G. Meade, Ed C. Lavelle   +8 more
doaj   +1 more source

Modulation of the host Th1 immune response in pigeon protozoal encephalitis caused by Sarcocystis calchasi [PDF]

, 2013
Pigeon protozoal encephalitis (PPE) is an emerging central-nervous disease of domestic pigeons (Columba livia f. domestica) reported in Germany and the United States.
Gruber, Achim D., Kaspers, Bernd, Klopfleisch, Robert, Lierz, Michael, Meyer, Anne, Olias, Philipp   +5 more
core   +3 more sources

Chemokinesis-Driven Accumulation of Active Colloids in Low-Mobility Regions of Fuel Gradients [PDF]

arXiv, 2020
Many motile cells exhibit migratory behaviors, such as chemotaxis (motion up or down a chemical gradient) or chemokinesis (when speed depends on concentration), which enable them to carry out vital functions including immune response, egg fertilization, and predator evasion.
arxiv  

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

M6A‐mediated upregulation of lncRNA TUG1 in liver cancer cells regulates the antitumor response of CD8+ T cells and phagocytosis of macrophages

Advanced Science
Tumor immune evasion relies on the crosstalk between tumor cells and adaptive/innate immune cells. Immune checkpoints play critical roles in the crosstalk, and immune checkpoint inhibitors have achieved promising clinical effects. The long non‐coding RNA
Qing Xi, Guangze Yang, Xue He, Hao Zhuang, Li Li, Bing Lin, Lingling Wang, Xianyang Wang, Chunqiang Fang, Qiurui Chen, Yongjie Yang, Zhaoan Yu, Hao Zhang, Wenqian Cai, Yan Li, Han Shen, Li Liu, Rongxin Zhang   +17 more
doaj   +1 more source

VirusPKT: A Search Tool For Assimilating Assorted Acquaintance For Viruses [PDF]

IJCSE Volume 1 Issue 3 2009 122-126, 2009
Viruses utilize various means to circumvent the immune detection in the biological systems. Several mathematical models have been investigated for the description of viral dynamics in the biological system of human and various other species. One common strategy for evasion and recognition of viruses is, through acquaintance in the systems by means of ...
arxiv  

Mapping spatial organization and genetic cell-state regulators to target immune evasion in ovarian cancer [PDF]

The drivers of immune evasion are not entirely clear, limiting the success of cancer immunotherapies. Here we applied single-cell spatial and perturbational transcriptomics to delineate immune evasion in high-grade serous tubo-ovarian cancer. To this end,
Aguirre, Karmen, Bassik, Michael C, Han, Lucy M, Howitt, Brooke E, Jerby, Livnat, Kim, Subin, Kim, Young-Min, Laveroni, Olivia, Liang, Brooke, Plevritis, Sylvia K, Snyder, Michael P, Valbuena, Raeline, Wang, Aihui, Yeh, Christine Yiwen, Zhang, Xiaoming   +14 more
core   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Selective recruitment of Th2-type cells and evasion from a cytotoxic immune response mediated by viral macrophage inhibitory protein-II [PDF]

, 2001
Kim S. C. Weber, Hermann-Josef Gröne, Martin Röcken, Christiane Klier, Songhai Gu, Rudolf Wank, Amanda E. I. Proudfoot, Peter J. Nelson, Christian Weber   +8 more
openalex   +2 more sources