Results 151 to 160 of about 121,779 (302)

Immune system evasion by peripheral nerve sheath tumor [PDF]

, 2006
Philip R. Lee, Jonathan E. Cohen, R. Douglas Fields   +2 more
openalex   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

The Function of TRIM25 in Antiviral Defense and Viral Immune Evasion. [PDF]

Viruses
Liu Q, Peng S, Wei J, Xie Z.
europepmc   +1 more source

Immune evasion proteins of human cytomegalovirus do not prevent a diverse CD8+ cytotoxic T-cell response in natural infection

, 2004
Thomas Manley, Lisa Luy, Thomas R. Jones, Michael Boeckh, Helen P. Mutimer, Stanley R. Riddell   +5 more
openalex   +1 more source

Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity

Advanced Science, EarlyView.
Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui, Zining Wang, Zixuan Guo, Hongxia Zhang, Yongxiang Liu, Huanling Zhang, Huan Jin, Feifei Xu, Xiaojuan Wang, Chunyuan Xie, Hui Guo, Tiantian Wang, Yanxun Lin, Qi Zhao, Penghui Zhou, Jing Tan, Jin‐Xin Bei, Peng Huang, Jinyun Liu, Xiaojun Xia   +19 more
wiley   +1 more source

Urea cycle dysregulation: a new frontier in cancer metabolism and immune evasion. [PDF]

Cell Commun Signal
Shou Y, Liu R, Xiong H, Xu K, Chen X, Huang L, Zhang Y, Sheng H, Zhang H, Lu Y.   +9 more
europepmc   +1 more source

Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1 [PDF]

, 2007
Paul A. Ramsland, Natasha Willoughby, Halina M. Trist, William Farrugia, P. Mark Hogarth, John D. Fraser, Bruce D. Wines   +6 more
openalex   +1 more source

METTL14‐Mediated M6A Modification of LINC01094 Induces Glucose Metabolic Reprogramming in Breast Cancer by Recruiting the PKM2/JMJD5 Complex

Advanced Science, EarlyView.
METTL14/IGF2BP2‐mediated m6A modification drives LINC01094 upregulation in BC. Then, LINC01094 interacts with PKM2 monomers to promote their dimerization, while serving as a flexible scaffold to facilitate the assembly of the PKM2/JMJD5 complex, synergistically stabilizing PKM2 dimers and enhancing their nuclear translocation.
Mengqi Wang, Zhaoxin Gao, Ruinan Zhao, Pan Zhou, Jingxi Chen, Hui Zhang, Yawen Wang, Wenjie Zhu, Peng Gao   +8 more
wiley   +1 more source

Immune Evasion Strategies

, 2018
M. Magdalena Aguirre-García, Laila Gutiérrez-Kobeh, ArturoA. Wilkins-Rodríguez, Alma Reyna Escalona-Montaño   +3 more
openaire   +4 more sources

Interpreting immune evasion: a novel assay for HLA loss detection. [PDF]

Front Immunol
Pettersson L, Westerling S, Ramezanali H, Vezzi F, Eckerud R, Hauzenberger D, Hedrum A, Mattsson J, Uhlin M, Uzunel M.   +9 more
europepmc   +1 more source