Harnessing Nanohybridized Niclosamide for Precision Mpox Therapeutics
Advanced Healthcare Materials, EarlyView.This study investigates the potential of nanohybridized niclosamide as a therapeutic agent for Mpox, focusing on enhanced bioavailability, improved antiviral efficacy, and controlled drug release achieved through nanoengineering. The research emphasizes significant advancements in formulation strategies, mechanistic insights, and therapeutic outcomes ...
N. Sanoj Rejinold +2 more
wiley +1 more source
Soluble Fas ligand released by colon adenocarcinoma cells induces host lymphocyte apoptosis: an active mode of immune evasion in colon cancer [PDF]
, 2001 Erwei Song +5 more
openalex +1 more source
Enhancing Ultrasound Power Transfer: Efficiency, Acoustics, and Future Directions
Advanced Materials, EarlyView.Implantable devices significantly enhance healthcare but are limited by battery life. Ultrasound power transfer technology offers a promising solution for sustainable operation. This review addresses gaps in current research, particularly in sound field analysis and energy efficiency optimization.
Yi Zheng +6 more
wiley +1 more source
Joint Modeling of Spatial Dependencies Across Multiple Subjects in Multiplexed Tissue Imaging [PDF]
arXivThe tumor microenvironment (TME) is a spatially heterogeneous ecosystem where cellular interactions shape tumor progression and response to therapy. Multiplexed imaging technologies enable high-resolution spatial characterization of the TME, yet statistical methods for analyzing multi-subject spatial tissue data remain limited.
arxiv
Increased Expression of Fas Ligand in Human Tuberculosis and Leprosy Lesions: a Potential Novel Mechanism of Immune Evasion in Mycobacterial Infection [PDF]
, 2001 Tehmina Mustafa +4 more
openalex +1 more source
Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
Securing Behavior-based Opinion Spam Detection [PDF]
arXiv, 2018 Reviews spams are prevalent in e-commerce to manipulate product ranking and customers decisions maliciously. While spams generated based on simple spamming strategy can be detected effectively, hardened spammers can evade regular detectors via more advanced spamming strategies.
arxiv
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Easy to Fool? Testing the Anti-evasion Capabilities of PDF Malware Scanners [PDF]
arXiv, 2019 Malware scanners try to protect users from opening malicious documents by statically or dynamically analyzing documents. However, malware developers may apply evasions that conceal the maliciousness of a document. Given the variety of existing evasions, systematically assessing the impact of evasions on malware scanners remains an open challenge.
arxiv
Micro‐ and Nano‐Bots for Infection Control
Advanced Materials, EarlyView.This review presents a strategic vision for integrating micro‐ and nanobots in the pipeline for infection diagnosis, prevention, and treatment. To develop these robots as a practical solution for infection management, their design principles are clarified based on their propulsion mechanisms and then categorized infection management domains based on ...
Azin Rashidy Ahmady +5 more
wiley +1 more source