Results 181 to 190 of about 1,940,572 (373)
Cancer cells effectively evade immune surveillance, not only through the well-known PD-1/PD-L1 pathway but also via alternative mechanisms that impair patient response to immune checkpoint inhibitors.
Ramiro Martinez+30 more
doaj +1 more source
Cellular dynamics of host-parasitoid interactions: Insights from the encapsulation process in a partially resistant host [PDF]
Cotesia typhae is an eastern African endoparasitoid braconid wasp that targets the larval stage of the lepidopteran stem borer, Sesamia nonagrioides, a maize crop pest in Europe. The French host population is partially resistant to the Makindu strain of the wasp, allowing its development in only 40% of the cases.
arxiv
Controlling tax evasion fluctuations [PDF]
We incorporate the behaviour of tax evasion into the standard two-dimensional Ising model and augment it by providing policy-makers with the opportunity to curb tax evasion via an appropriate enforcement mechanism. We discuss different network structures in which tax evasion may vary greatly over time if no measures of control are taken.
arxiv
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou+10 more
wiley +1 more source
Achieving Optimal Health With Host‐Directed Therapies (HDTs) in Infectious Diseases—A New Horizon
Host‐directed therapies (HDTs) represent a transformative approach in infectious disease management by targeting host factors to enhance immune responses and inhibit viral replication. This innovative strategy leverages advanced genomics and gene editing technologies, offering promising avenues for improved patient outcomes and a new horizon in ...
Amol D. Gholap+10 more
wiley +1 more source
An Immune Evasion Mechanism for Spirochetal Persistence in Lyme Borreliosis [PDF]
Fang Ting Liang+3 more
openalex +1 more source
Clinically Relevant Metallic Nanoparticles in Tuberculosis Diagnosis and Therapy
Tuberculosis (TB) remains a global health challenge, with drug‐resistant strains exacerbating the issue. Metallic nanoparticles (MNPs) show promise in TB diagnosis as sensor probes and in combination therapy with antimycobacterial drugs, requiring further pre‐clinical and clinical research for clinical translation.
Christianah Aarinola Akinnawo+1 more
wiley +1 more source
Penicillin‐binding proteins in Streptococcus agalactiae: a novel mechanism for evasion of immune clearance [PDF]
Amanda L. Jones+4 more
openalex +1 more source
Opportunities in Therapeutic mRNA Stabilization: Sequence, Structure, Adjuvants and Vectors
Current mRNA lipid nanoparticles rely on cold storage, which increases the cost and reduces access to the vaccines. As mRNA expands to other clinical opportunities, better methods to stabilize the medicines during shipping, storage, and delivery are needed.
Joshua A. Choe+4 more
wiley +1 more source
The MYC oncogene — the grand orchestrator of cancer growth and immune evasion
R. Dhanasekaran+5 more
semanticscholar +1 more source