Results 191 to 200 of about 241,317 (354)

MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1

, 2019
Hui Li, Chia‐Wei Li, Xiaoqiang Li, Qingqing Ding, Lei Guo, Shuang Liu, Chunxiao Liu, Chien‐Chen Lai, Jung-Mao Hsu, Qiongzhu Dong, Weiya Xia, Jennifer L. Hsu, Hirohito Yamaguchi, Yi Du, Yun‐Ju Lai, Xian Wen Sun, Paul Koller, Qing‐Hai Ye, Mien‐Chie Hung   +18 more
openalex   +2 more sources

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Supplementary Figure 2 from Ectopic Expression of Vascular Cell Adhesion Molecule-1 as a New Mechanism for Tumor Immune Evasion [PDF]

, 2023
Ken-Yu Lin, Dan Lu, Chien‐Fu Hung, Shiwen Peng, Lanqing Huang, Chunfa Jie, Francisco Javier Murillo, Jesse W. Rowley, Ya-Chea Tsai, Liangmei He, Dae‐Jin Kim, Elizabeth M. Jaffee, Drew M. Pardoll, T.-C. Wu   +13 more
openalex   +1 more source

A Unique Chimeric RNA: ERCC1‐iASPP Drives Benzo[a]pyrene‐Induced Lung Carcinogenesis via Dual Coding and Non‐Coding Mechanisms

Advanced Science, EarlyView.
The chimeric RNA ERCC1‐iASPP possesses dual coding and non‐coding functions, synergistically accelerating the process of cellular malignant transformation. Abstract Genetic variation at 19q13.3 critically modulates chemical carcinogen‐induced lung carcinogenesis, particularly in mediating the activity of benzo[a]pyrene (B[a]P), a major polycyclic ...
Mingming Shan, Mingyang Xiao, Liang Zhang, Shen Wang, Jiahang Wu, Kang Cao, Yujin Li, Guopei Zhang, Junwei Xie, Xiaobo Lu   +9 more
wiley   +1 more source

Spatiotemporal dynamics of Brucella immune evasion across infection stages. [PDF]

Front Immunol
Su Y, Zhang L, Liu R, Sa R, Zheng L.
europepmc   +1 more source

Deletion of immune evasion genes provides an effective vaccine design for tumor-associated herpesviruses [PDF]

, 2020
Gurpreet Brar, Nisar Farhat, Alisa Sukhina, Alex K. Lam, Yong‐Hoon Kim, Tiffany Hsu, Leming Tong, Wai Lin, Carl F. Ware, Marcia A. Blackman, Ren Sun, Ting-Ting Wu   +11 more
openalex   +1 more source

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Monocytes and immune evasion strategies in HIV: Unraveling the intricacies. [PDF]

Medicine (Baltimore)
Obeagu EI, Obeagu GU.
europepmc   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

TDP2 drives immune evasion and metastatic progression in prostate cancer. [PDF]

PLoS One
Cao H, Pan A, Chen Y, Zheng F.
europepmc   +1 more source