Results 261 to 270 of about 121,779 (302)
LIMD1 Loss as an Early Driver of PD-L1 Upregulation and Immune Evasion in Lung Cancer
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Annual Review of Immunology, 2003
Large DNA viruses defend against hostile assault executed by the host immune system by producing an array of gene products that systematically sabotage key components of the inflammatory response. Poxviruses target many of the primary mediators of innate immunity including interferons, tumor necrosis factors, interleukins, complement, and chemokines ...
Joanna Sypula+9 more
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Large DNA viruses defend against hostile assault executed by the host immune system by producing an array of gene products that systematically sabotage key components of the inflammatory response. Poxviruses target many of the primary mediators of innate immunity including interferons, tumor necrosis factors, interleukins, complement, and chemokines ...
Joanna Sypula+9 more
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Immune evasion by adenoviruses
Immunological Reviews, 1999Summary: .Adenovirus is a human pathogen that infects mainly respiratory and gastrointestinal epithelia. While the pathology caused by this virus is generally not life threatening in immunocompetent individuals, there is a large literature describing its ability to establish a persistent infection.
Linda R. Gooding, Jeffrey A. Mahr
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The glycocalyx and immune evasion in cancer
The FEBS Journal, 2021In order to establish malignant lesions, tumors must first evade their detection by immune cells. Tumors achieve this by embellishing and tailoring their glycocalyx, a network of polysaccharides and glycosylated proteins that refracts the phagocytic efforts of myeloid cells, shrouds neoantigens and other ligands from cells of the acquired immune system,
Sina Ghasempour, Spencer A. Freeman
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Cytomegalovirus Immune Evasion
2008Human cytomegalovirus (HCMV) has become a paradigm for viral immune evasion due to its unique multitude of immune-modulatory strategies. HCMV modulates the innate as well as adaptive immune response at every step of its life cycle. It dampens the induction of antiviral interferon-induced genes by several mechanisms. Further striking is the multitude of
Daniel Malouli+3 more
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Herpesviruses and immunity: The art of evasion
Veterinary Microbiology, 2010Herpesviruses have evolved several effective strategies to counter the host immune response. Chief among these is inhibition of the host MHC class I antigen processing and presentation pathway, thereby reducing the presentation of virus-derived epitopes on the surface of the infected cell.
Bryan D. Griffin+3 more
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Immune evasion by staphylococci
Nature Reviews Microbiology, 2005Staphylococcus aureus can cause superficial skin infections and, occasionally, deep-seated infections that entail spread through the blood stream. The organism expresses several factors that compromise the effectiveness of neutrophils and macrophages, the first line of defence against infection. S.
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2014
This chapter examines several mechanisms by which two well-known protozoan pathogens, one extracellular and one intracellular, successfully evade host immunity. It discusses how one protozoan parasite has evolutionarily addressed few problems by displaying a highly ordered molecular surface coat that serves largely to protect therypanosome plasma ...
Martin Olivier, John M. Mansfield
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This chapter examines several mechanisms by which two well-known protozoan pathogens, one extracellular and one intracellular, successfully evade host immunity. It discusses how one protozoan parasite has evolutionarily addressed few problems by displaying a highly ordered molecular surface coat that serves largely to protect therypanosome plasma ...
Martin Olivier, John M. Mansfield
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Immune evasion strategies of flaviviruses
Vaccine, 2013Flavivirus is a genus of the family Flaviviridae. It includes West Nile virus (WNV), dengue virus (DENV), yellow fever virus (YFV), Japanese encephalitis virus (JEV), tick-borne encephalitis virus (TBEV), and several other viruses which lead to extensive morbidity and mortality in humans.
Zhen F. Fu+5 more
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