Results 271 to 280 of about 121,779 (302)
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Future Virology, 2005
Through eons of co-evolution, poxviruses and their hosts have come to an elegant point of equilibrium whereby the host immune system is systematically modulated in favor of the virus. Owing to the large coding capacity of poxviruses, many gene products are dedicated as virulence factors.
Steven H. Nazarian, Grant McFadden
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Through eons of co-evolution, poxviruses and their hosts have come to an elegant point of equilibrium whereby the host immune system is systematically modulated in favor of the virus. Owing to the large coding capacity of poxviruses, many gene products are dedicated as virulence factors.
Steven H. Nazarian, Grant McFadden
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Immunological Reviews, 1997
SummaryVaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include proteins which oppose apoptosis. Synthesise steroids, capture chemokines, counteract complement, interfere with interferon and intercept ...
Antonio Alcami +4 more
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SummaryVaccinia virus and other poxviruses express a wide variety of proteins which are nonessential for virus replication in culture but help the virus to evade the host response to infection. Examples include proteins which oppose apoptosis. Synthesise steroids, capture chemokines, counteract complement, interfere with interferon and intercept ...
Antonio Alcami +4 more
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Science, 2011
Pattern recognition receptors are critical to allow cells to sense invading viruses and initiate antiviral immune responses, but viruses deploy a myriad of tactics to avoid detection and induction of antiviral immunity. Gregory et al. (p.
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Pattern recognition receptors are critical to allow cells to sense invading viruses and initiate antiviral immune responses, but viruses deploy a myriad of tactics to avoid detection and induction of antiviral immunity. Gregory et al. (p.
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2014
This chapter focuses on the study of viral immune evasion. Most viruses spread from one host to the next via secreted bodily fluids; to gain access to their target cells for replication they need to cross epithelial barriers, which can be considered the first line of host defense.
Ann B. Hill +2 more
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This chapter focuses on the study of viral immune evasion. Most viruses spread from one host to the next via secreted bodily fluids; to gain access to their target cells for replication they need to cross epithelial barriers, which can be considered the first line of host defense.
Ann B. Hill +2 more
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Viral Strategies of Immune Evasion
Science, 1998The vertebrate body is an ideal breeding ground for viruses and provides the conditions that promote their growth, survival, and transmission. The immune system evolved and deals with this challenge. Mutually assured destruction is not a viable evolutionary strategy; thus, the study of host-virus interactions provides not only a glimpse of life at ...
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Immune Evasion in Ebolavirus Infections
Viral Immunology, 2015Ebola virus (EBOV) infects humans as well as several animal species. It can lead to a highly lethal disease, with mortality rates approaching 90% in primates. Recent advances have deepened our understanding of how this virus is able to prevent the development of protective immune responses.
Gary P. Kobinger, Jonathan Audet
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Immune evasion by gamma-herpesviruses
Current Opinion in Immunology, 2004Persistent viruses, such as herpesviruses, transmit infection by evading cytotoxic T cells during lytic replication. The gamma-herpesviruses additionally evade T cells during the proliferation of latently infected lymphocytes to establish a persistent viral reservoir.
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Staphylococcal innate immune evasion
Trends in Microbiology, 2005Upon entering the human body, bacteria are confronted with the sophisticated innate defense mechanisms of the human host. From work in recent years it has become obvious that a new and growing family of small and excreted proteins can counteract the antibacterial effects of innate immunity.
Kok P. M. van Kessel +2 more
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Trends in Microbiology, 1998
Advances in T cell immunology and the use of transgenic mice for in vivo studies have highlighted the major importance of T cells in antiviral immunity. However, we often forget the humoral immune response and how it can modulate viral pathogenesis. Herpes simplex virus (HSV) expresses a human immunoglobulin G (IgG) Fc receptor (FcγR) that is composed ...
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Advances in T cell immunology and the use of transgenic mice for in vivo studies have highlighted the major importance of T cells in antiviral immunity. However, we often forget the humoral immune response and how it can modulate viral pathogenesis. Herpes simplex virus (HSV) expresses a human immunoglobulin G (IgG) Fc receptor (FcγR) that is composed ...
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Immune evasion by designer microrobots
Science Robotics, 2020Recent work is unveiling the interactions between magnetic microswimmers and cells of the immune system.
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