Results 301 to 310 of about 1,940,572 (373)

Redefining bladder cancer treatment: innovations in overcoming drug resistance and immune evasion. [PDF]

Front Immunol
Huang P, Wang J, Yu Z, Lu J, Sun Z, Chen Z.   +5 more
europepmc   +1 more source

Biomimetic Nanoplatform for Targeted Rheumatoid Arthritis Therapy: Modulating Macrophage Niches Through Self‐Sustaining Positive Feedback‐Driven Drug Release Mechanisms

Advanced Science, EarlyView.
Rheumatoid arthritis is an incurable inflammatory autoimmune disease. The cleverly biomimetic nanoplatform integrates nanoenzymes and gene therapeutics and is sequentially modified by guanidinium‐based polymers and macrophage membranes, enhancing the gene silencing capability and reactive oxygen species scavenging efficiency through self‐sustaining ...
Huichao Xie, Xiaoyu Huang, Bao Li, Yongfeng Chen, Haoran Niu, Tong Yu, Shimei Yang, Shuxin Gao, Yutong Zeng, Tianzhi Yang, Yan Kang, Keda Zhang, Pingtian Ding   +12 more
wiley   +1 more source

Faculty Opinions recommendation of A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system.

, 2007
Francisco Garcı́a-del Portillo
openalex   +2 more sources

Cracking the Codes behind Cancer Cells' Immune Evasion. [PDF]

Int J Mol Sci
Mundhara N, Sadhukhan P.
europepmc   +1 more source

Identification and Biological Evaluation of a Novel CLK4 Inhibitor Targeting Alternative Splicing in Pancreatic Cancer Using Structure‐Based Virtual Screening

Advanced Science, EarlyView.
Pancreatic cancer is a highly aggressive malignancy with limited treatment options. CLK4 regulates alternative splicing, contributing to cancer progression. This study establishes a computational model to identify CLK4 inhibitors, leading to compound 150441 (IC50: 21.4 nm).
Chun‐Lin Yang, Yi‐Wen Wu, Huang‐Ju Tu, Yun‐Hsuan Yeh, Tony Eight Lin, Tzu‐Ying Sung, Mu‐Chun Li, Shih‐Chung Yen, Jui‐Hua Hsieh, Ming‐Chin Yu, Sen‐Yung Hsieh, Hsing‐Pang Hsieh, Shiow‐Lin Pan, Kai‐Cheng Hsu   +13 more
wiley   +1 more source

Ubiquitination Enzymes in Cancer, Cancer Immune Evasion, and Potential Therapeutic Opportunities. [PDF]

Cells
Awan AB, Osman MJA, Khan OM.
europepmc   +1 more source

Assembly and Functionality of 2D Protein Arrays

Advanced Science, EarlyView.
2D protein arrays‐based outstanding properties, including their remarkable structural stability, exceptional physiochemical properties, and tunable electronic and mechanical attributes, have become a key functional platform for developing advanced functional materials.
Mingming Du, Fanmeng Zeng, YueFei Wang, Ying Li, Guangcun Chen, Jiang Jiang, Qiangbin Wang   +6 more
wiley   +1 more source

The Role of vIL-6 in KSHV-Mediated Immune Evasion and Tumorigenesis. [PDF]

Viruses
Komaki S, Inagaki T, Kumar A, Izumiya Y.
europepmc   +1 more source

Targeted STING Activation Using Modified Ultrasound‐Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma

Advanced Science, EarlyView.
This study explores the use of ultrasound contrast agents loaded with Stimulator of Interferon Genes (STING) agonists as an approach to activate the body's immune system against cancer. Termed Microbubble‐assisted UltraSound‐guided Immunotherapy of Cancer (MUSIC), this strategy effectively inhibits tumor growth and improves survival in mouse models of ...
Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L. Edwards, Nicole McCuen, Prasanna G. Alluri, Betty Y.S. Kim, Wen Jiang, Jacques Lux   +12 more
wiley   +1 more source

Research Progress on Immune Evasion of Mycoplasma hyopneumoniae. [PDF]

Microorganisms
Jiang B, Zhang Y, Li G, Quan Y, Shu J, Feng H, He Y.   +6 more
europepmc   +1 more source