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Placenta immune infiltrates and perinatal outcomes

American Journal of Reproductive Immunology, 2018
Pregnancy is a state of immunotolerance and loss of this immunotolerance may lead to fetal rejection, pregnancy complications, and neonatal complications. Immunobiology of pregnancy is complex and involves unique immune cell populations specific to pregnancy, changes in mucosal immune cells and peripheral immune system, and reciprocal adaptations ...
Maide Ozen   +2 more
openaire   +2 more sources

Immune Cell Infiltration in Feline Meningioma

Journal of Comparative Pathology, 2017
Meningioma is the most common primary brain tumour in the cat. Although most of these tumours are considered to be benign based on histological characteristics, little is known regarding microenvironmental changes associated with the tumour. The characterization of the immune-cell infiltrate in human and canine meningiomas has been described; however ...
Andrew D. Miller   +3 more
openaire   +3 more sources

CCL21-induced immune cell infiltration

International Immunopharmacology, 2007
Cellular immune responses can be initiated via peptide presentation by specialized antigen presenting cells, dendritic cells (DCs), which stimulate naïve T cells. The trafficking of DCs and T cells is regulated by chemokines such as CCL21. CCL21 is normally expressed in the lymphoid organs and coordinates the interactions between DCs and T cells ...
James E. Talmadge   +5 more
openaire   +2 more sources

A multiplexed view of immune infiltration

Nature Reviews Cancer, 2018
Keren et al. have used multiplexed imaging in intact samples from breast cancer patients to gain insights into the architecture of the tumour immune microenvironment.
openaire   +3 more sources

The immune cell infiltrate in the microenvironment of vulvar Paget disease

Gynecologic Oncology, 2018
Non-invasive vulvar Paget disease (VPD) is a rare skin disorder mainly affecting elderly women. Recently, the immune modulator imiquimod was reported as an effective treatment option. Knowledge about the immune microenvironment of VPD is lacking.This study investigates the basic characteristics of the immune infiltrate in VPD (n = 10); moreover the ...
van der Linden, M.   +9 more
openaire   +4 more sources

Variability in immune infiltrates and HLA expression in cholangiocarcinoma.

Journal of Clinical Oncology, 2014
230 Background: Cholangiocarcinoma continues to have a dismal prognosis. The lack of effective therapy prompted us to determine whether patients develop an immune response against their own tumors. The aim of this study is to evaluate the CD8 infiltrate and expression of HLA class I antigen processing machinery (APM) components in cholangiocarcinoma.
Sabbatino, Francesco   +11 more
openaire   +3 more sources

Immune Responses in Rabbits With Phlyctenules and Catarrhal Infiltrates

Archives of Ophthalmology, 1983
Corneal phlyctenules and catarrhal infiltrates developed in rabbits immunized with Staphylococcus aureus cell walls (CWs) mixed with complete Freund's adjuvant (CFA) after topical challenge with viable S aureus. The immune responses of these rabbits to CWs and ribitol teichoic acid (RTA) before and after immunization with CW/CFA were studied and the ...
Bartly J. Mondino   +2 more
openaire   +3 more sources

Decidual Immune Cell Infiltrate in Hydatidiform Mole

Cancer Investigation, 2009
Hydatidiform mole is a gestational trophoblastic disease characterized by proliferation of the pregnancy-associated trophoblastic tissue. Complete hydatidiform mole is an entirely paternally derived lesion, and therefore, represents complete intrauterine allografts that can induce an altered maternal immune response Hypothesis: Here, we hypothesize ...
Mahmoud R. Hussein   +3 more
openaire   +3 more sources

Single‐cell RNA sequencing and lipidomics reveal cell and lipid dynamics of fat infiltration in skeletal muscle

Journal of Cachexia, Sarcopenia and Muscle, 2021
Teresa G Valencak   +2 more
exaly  

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