Results 151 to 160 of about 128,938 (315)
Advanced Science, EarlyView.These findings reveal that silicon exerts strong protective effects in diabetic bone defect models by selectively promoting Drp1‐Mff activity. Silicon facilitates precise regulation of mitochondrial dynamics to enable functional mitochondrial transfer.
Yu‐Xuan Ma +12 more
wiley +1 more source
CD8+ T cell memory is sustained in mice by hepatic stellate cells
Hepatology, EarlyView., 2022 HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen +4 more
wiley +1 more source
Reconstitution of EBV-Specific T Cell Immunity in Solid Organ Transplant Recipients [PDF]
, 1998 Tanzina Haque +8 more
openalex +1 more source
Development of MDM2‐Targeting PROTAC for Advancing Bone Regeneration
Advanced Science, EarlyView.This work presents a creative pipeline for developing MDM2‐targeting PROTACs (MDM2‐PROTACs) for application in bone regeneration. The developed PROTACs (CL144 and CL174) are validated for their degradation efficiency and osteogenic effects in human BMSCs.
Sol Jeong +17 more
wiley +1 more source
Hemophagocytic Lymphohistiocytosis in an AIDS Patient with Kaposi Sarcoma: A Treatment Dilemma
Case Reports in Hematology, 2019 Hemophagocytic lymphohistiocytosis (HLH) is a result of an abnormal activation of immune cells (T lymphocytes, natural killer cells, and macrophages) resulting in cytokine overproduction and immune destruction of cells, eventually resulting in multiorgan
Oluwadunni E. Emiloju +3 more
doaj +1 more source
SKEWING OF THE T CELL REPERTOIRE TOWARD A TARGET ANTIGEN DURING A PERIOD OF T CELL IMMUNE RECONSTITUTION. • 935 [PDF]
, 1996 Crystal L. Mackall, Ronald E. Gress
openalex +1 more source
Acute Renal Failure on Immune Reconstitution in an HIV-Positive Patient with Miliary Tuberculosis [PDF]
, 2017 Immune reconstitution syndrome following HAART in human immunodeficiency virus (HIV)-infected patients is characterized by inflammatory worsening of organ functions despite improvement in HIV surrogate markers of HIV infection. We describe a patient with
Battegay, Manuel +7 more
core
Advanced Science, EarlyView.Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu +21 more
wiley +1 more source
Functional Reconstitution of Class II MHC-Restricted T Cell Immunity Mediated by Retroviral Transfer of the αβ TCR Complex [PDF]
, 2000 Keishi Fujio +8 more
openalex +1 more source
Advanced Science, EarlyView.Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi +14 more
wiley +1 more source