Results 191 to 200 of about 26,269 (228)
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Immune reconstitution inflammatory syndrome in HIV
Current Opinion in Infectious Diseases, 2006The purpose of this review is to describe the epidemiology, clinical features, putative immune mechanisms and management of immune reconstitution inflammatory syndrome (IRIS) using data published in the last 2 years.Ever more conditions are reported as IRIS events.
Marc, Lipman, Ronan, Breen
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Immune reconstitution inflammatory syndrome
2021This chapter examines how treatment with antiretroviral therapy (ART) results in a decreased HIV viral load for the majority of patients with HIV disease. It talks about the early stages of immune recovery on ART, in which a subset of patients may experience clinical deterioration due to the immune reconstitution inflammatory syndrome (IRIS).
Suzaan Marais, Graeme Meintjes
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Management of the Immune Reconstitution Inflammatory Syndrome
Current HIV/AIDS Reports, 2012The immune reconstitution inflammatory syndrome (IRIS) is a frequent early complication of antiretroviral therapy (ART) in patients with advanced HIV. Because there is no confirmatory diagnostic test, the diagnosis is based on clinical presentation and exclusion of alternative causes for deterioration, such as antimicrobial drug resistance ...
Graeme, Meintjes +2 more
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Cryptococcal immune reconstitution inflammatory syndrome
Current Opinion in Infectious Diseases, 2013The epidemiology and pathogenesis of, and risk factors for, cryptococcal immune reconstitution inflammatory syndrome (CM-IRIS) are reviewed with an emphasis on how new insights inform a rational management approach and prevention strategies.Risk factors for paradoxical CM-IRIS are a low inflammatory response and CD4 cell count at baseline, rapid immune
Nicky, Longley +2 more
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Ocular immune reconstitution inflammatory syndromes
Current Opinion in HIV and AIDS, 2008The aim of this article is to review the current literature concerning immune reconstitution inflammatory syndrome in relation to the eye. The definition, epidemiology, pathophysiology, risk factors, clinical features, diagnosis and treatment are discussed.Immune reconstitution inflammatory syndrome affecting the eye has been documented in association ...
Otiti-Sengeri, J. +3 more
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Paradoxical immune reconstitution inflammatory syndrome in neurotuberculosis
BMJ Case Reports, 2021Tuberculosis (TB) remains the most common infection in developing countries and India contributes the maximum number of cases to the global burden. Primary healthcare physicians across the country face major challenges in diagnosis and treatment of childhood TB.
Seema Pavaman Sindgikar +3 more
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Immune Reconstitution Inflammatory Syndrome
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007Immune reconstitution inflammatory syndrome (IRIS), also called immune restoration disease, occurs in a subset of HIV-infected patients after the initiation of highly active antiretroviral therapy (HAART) and can be diagnostically challenging and difficult to treat.
Shyam Sundar +3 more
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Coping with TB immune reconstitution inflammatory syndrome
Expert Review of Respiratory Medicine, 2009The TB immune reconstitution inflammatory syndrome (IRIS) is a relatively frequent complication in HIV-TB-coinfected patients after they start highly active antiretroviral therapy (HAART). There are two forms of TB IRIS: the 'paradoxical' type (clinical worsening of a patient on TB treatment) and the 'unmasking' type (undiagnosed TB becoming apparent ...
Robert Colebunders, Harriet Kisembo
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CNS immune reconstitution inflammatory syndrome
2018Immune reconstitution inflammatory syndrome (IRIS) describes a syndrome of aberrant reconstituted immunity, often in association with HIV infection, beginning with a normalization of CD4+ T-cell counts resulting in a dysregulated immune response against an infecting opportunistic pathogen and the host.
Lauren, Bowen +2 more
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Association of nephrotic syndrome with immune reconstitution inflammatory syndrome
Pediatric Nephrology, 2011Up to 50% of patients with severe immune deficiency experience an excessive inflammatory response called immune reconstitution inflammatory syndrome (IRIS) after the initiation of antiretroviral therapy (ART). IRIS has been observed after various opportunistic infections with pathogens such as mycobacteria, including Bacille Calmette-Guérin ...
Lankisch, Petra +5 more
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