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Immune Reconstitution Inflammatory Syndrome
Advances in Dental Research, 2011 Immune reconstitution inflammatory syndrome (IRIS) is a phenomenon observed in patients recovering from immunodeficiency. The clinical presentation of IRIS involves the unmasking of covert infections or the worsening of overt conditions. Several causes and pathways have been suggested, most recognizing an inflammatory flare component occurring in the ...
Anwar R Tappuni
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Cryptococcal immune reconstitution inflammatory syndrome
Current Opinion in Infectious Diseases, 2013 The epidemiology and pathogenesis of, and risk factors for, cryptococcal immune reconstitution inflammatory syndrome (CM-IRIS) are reviewed with an emphasis on how new insights inform a rational management approach and prevention strategies.Risk factors for paradoxical CM-IRIS are a low inflammatory response and CD4 cell count at baseline, rapid immune
Nicky, Longley +2 more
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Immune Reconstitution Inflammatory Syndrome
, 2017 Immune reconstitution inflammatory syndrome (IRIS) is associated with either worsening of a recognized infection (paradoxical IRIS) or an unrecognized infection (unmasking IRIS), which occurs in the setting of improved immunologic function. Most patients presenting with IRIS should be maintained on antiretroviral therapy (ART) along with treatment for ...
Dagan Coppock, William R. Short
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HIV-1 tuberculosis-associated immune reconstitution inflammatory syndrome [PDF]
Seminars in Immunopathology, 2015 Patients co-infected with HIV-1 and tuberculosis (TB) are at risk of developing TB-associated immune reconstitution inflammatory syndrome (TB-IRIS) following commencement of antiretroviral therapy (ART).
Graeme Meintjes +2 more
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Immune reconstitution inflammatory syndrome
International Journal of STD & AIDS, 2009Antiretroviral therapy (ART) inhibits HIV replication, allowing recovery of CD4+ T cell numbers and the restoration of immune function; its introduction has led to improved outcomes for individuals with HIV infection. However, it has been observed that some individuals responding to ART experience a clinical deterioration with symptoms and signs of an
J W T, Elston, H, Thaker
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Immune reconstitution inflammatory syndrome in HIV
Current Opinion in Infectious Diseases, 2006The purpose of this review is to describe the epidemiology, clinical features, putative immune mechanisms and management of immune reconstitution inflammatory syndrome (IRIS) using data published in the last 2 years.Ever more conditions are reported as IRIS events.
Marc, Lipman, Ronan, Breen
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Management of the Immune Reconstitution Inflammatory Syndrome
Current HIV/AIDS Reports, 2012The immune reconstitution inflammatory syndrome (IRIS) is a frequent early complication of antiretroviral therapy (ART) in patients with advanced HIV. Because there is no confirmatory diagnostic test, the diagnosis is based on clinical presentation and exclusion of alternative causes for deterioration, such as antimicrobial drug resistance ...
Graeme, Meintjes +2 more
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Immune Reconstitution Inflammatory Syndrome
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2007Immune reconstitution inflammatory syndrome (IRIS), also called immune restoration disease, occurs in a subset of HIV-infected patients after the initiation of highly active antiretroviral therapy (HAART) and can be diagnostically challenging and difficult to treat.
Shyam Sundar +3 more
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Ocular immune reconstitution inflammatory syndromes
Current Opinion in HIV and AIDS, 2008The aim of this article is to review the current literature concerning immune reconstitution inflammatory syndrome in relation to the eye. The definition, epidemiology, pathophysiology, risk factors, clinical features, diagnosis and treatment are discussed.Immune reconstitution inflammatory syndrome affecting the eye has been documented in association ...
Otiti-Sengeri, J. +3 more
openaire +4 more sources