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Pulmonary manifestations of the immune reconstitution inflammatory syndrome
Current Opinion in Pulmonary Medicine, 2011Immune reconstitution inflammatory syndrome (IRIS) is a common occurrence in HIV patients starting antiretroviral therapy (ART), and pulmonary involvement is an important feature of tuberculosis-IRIS and pneumocystis-IRIS. Pulmonologists need an awareness of the timing, presentation and treatment of pulmonary IRIS.Case definitions for tuberculosis-IRIS
Gregory, Calligaro +2 more
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Cryptococcal Chorioretinitis with Immune Reconstitution Inflammatory Syndrome
Ocular Immunology and Inflammation, 2009Immune Reconstitution Inflammatory Syndrome (IRIS) is an inflammatory syndrome in the context of immune restoration directed at a specific infectious antigen despite resolution of infection, often associated with opportunistic infections. IRIS has been reported in 30% to 35% of HIV patients who have cryptococcosis in whom antiretroviral therapy was ...
Julia, Shulman +5 more
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Immune Reconstitution Inflammatory Syndrome and Tropical Dermatoses
Dermatologic Clinics, 2011The human immunodeficiency virus (HIV) pandemic has disproportionately affected tropical regions of the world, where dermatoses, such as leprosy and leishmaniasis, rarely encountered in temperate climates, are endemic. Although the introduction of highly active antiretroviral therapy (HAART) has been lifesaving, a few patients undergoing HAART ...
Erin Huiras, Amerson, Toby A, Maurer
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Cutaneous manifestations of immune reconstitution inflammatory syndrome
Current Opinion in HIV and AIDS, 2008The introduction of highly active antiretroviral therapy (HAART) has altered the pattern of dermatologic disease among HIV-infected patients. While the majority benefit substantially from highly active antiretroviral therapy-induced immune recovery, a subset of patients experience unmasking of new skin disease or paradoxical worsening of existing ...
Erin, Huiras +3 more
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Management of patients with the immune reconstitution inflammatory syndrome
Current HIV/AIDS Reports, 2009A significant proportion of patients present with the immune reconstitution inflammatory syndrome (IRIS) after commencing antiretroviral therapy (ART). This syndrome is most frequently associated with infective causes. The lack of evidence-based treatment guidelines poses challenges in the management of these patients.
Suzaan, Marais +3 more
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Dermatologic Manifestations of the Immune Reconstitution Inflammatory Syndrome
Dermatologic Clinics, 2006The immune reconstitution inflammatory syndrome (IRIS) represents a diverse range of immunopathologic reactions resulting in clinical deterioration that may occur as immune function is partially restored in HIV-infected patients receiving highly active antiretroviral therapy.
Rannakoe, Lehloenya, Graeme, Meintjes
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The Immune Reconstitution Inflammatory Syndrome: A Clinical Update
Current Infectious Disease Reports, 2012The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infections.
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The immune reconstitution inflammatory syndrome.
AIDS reviews, 2003The use of highly active antiretroviral therapy (HAART) has led to a substantial decrease in the frequency of opportunistic infections among HIV-infected individuals, along with a significant reduction in their mortality rate. However, a subgroup of HAART-treated patients will exhibit paradoxical deterioration in their clinical status, despite ...
Samuel A, Shelburne, Richard J, Hamill
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Immune Reconstitution Inflammatory Syndrome
2020null Bernardo Correia de Almeida Teixeira +1 more
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