Results 201 to 210 of about 26,269 (228)
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Immune Reconstitution Inflammatory Syndrome
2017Immune reconstitution inflammatory syndrome (IRIS) is associated with either worsening of a recognized infection (paradoxical IRIS) or an unrecognized infection (unmasking IRIS), which occurs in the setting of improved immunologic function. Most patients presenting with IRIS should be maintained on antiretroviral therapy (ART) along with treatment for ...
Dagan Coppock, William R. Short
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Pulmonary manifestations of the immune reconstitution inflammatory syndrome
Current Opinion in Pulmonary Medicine, 2011Immune reconstitution inflammatory syndrome (IRIS) is a common occurrence in HIV patients starting antiretroviral therapy (ART), and pulmonary involvement is an important feature of tuberculosis-IRIS and pneumocystis-IRIS. Pulmonologists need an awareness of the timing, presentation and treatment of pulmonary IRIS.Case definitions for tuberculosis-IRIS
Gregory, Calligaro +2 more
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Immune Reconstitution Inflammatory Syndrome and Tropical Dermatoses
Dermatologic Clinics, 2011The human immunodeficiency virus (HIV) pandemic has disproportionately affected tropical regions of the world, where dermatoses, such as leprosy and leishmaniasis, rarely encountered in temperate climates, are endemic. Although the introduction of highly active antiretroviral therapy (HAART) has been lifesaving, a few patients undergoing HAART ...
Erin Huiras, Amerson, Toby A, Maurer
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The immune reconstitution inflammatory syndrome and antiretroviral therapy
British Journal of Hospital Medicine, 2010Although generally mild, severe immune reconstitution inflammatory syndrome may complicate antiretroviral therapy, and it may be difficult to differentiate from treatment failure or toxicity. This article looks at diagnostic and therapeutic challenges of severe infectious manifestations of immune reconstitution inflammatory syndrome.
Lorent, N. +2 more
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Management of patients with the immune reconstitution inflammatory syndrome
Current HIV/AIDS Reports, 2009A significant proportion of patients present with the immune reconstitution inflammatory syndrome (IRIS) after commencing antiretroviral therapy (ART). This syndrome is most frequently associated with infective causes. The lack of evidence-based treatment guidelines poses challenges in the management of these patients.
Suzaan, Marais +3 more
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Cryptococcal Chorioretinitis with Immune Reconstitution Inflammatory Syndrome
Ocular Immunology and Inflammation, 2009Immune Reconstitution Inflammatory Syndrome (IRIS) is an inflammatory syndrome in the context of immune restoration directed at a specific infectious antigen despite resolution of infection, often associated with opportunistic infections. IRIS has been reported in 30% to 35% of HIV patients who have cryptococcosis in whom antiretroviral therapy was ...
Julia, Shulman +5 more
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Cutaneous manifestations of immune reconstitution inflammatory syndrome
Current Opinion in HIV and AIDS, 2008The introduction of highly active antiretroviral therapy (HAART) has altered the pattern of dermatologic disease among HIV-infected patients. While the majority benefit substantially from highly active antiretroviral therapy-induced immune recovery, a subset of patients experience unmasking of new skin disease or paradoxical worsening of existing ...
Erin, Huiras +3 more
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Graves' Immune Reconstitution Inflammatory Syndrome in Childhood
Thyroid, 2013The use of hematopoietic stem cell transplantations (HSCTs) as a curative therapy for life-threatening immunodeficiencies has had a profound impact on clinical outcomes. A subset of patients may experience immune reconstitution inflammatory syndrome (IRIS) post-transplant affecting the thyroid gland, but this has received little attention in the ...
Sinha A +5 more
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The Immune Reconstitution Inflammatory Syndrome: A Clinical Update
Current Infectious Disease Reports, 2012The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infections.
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The immune reconstitution inflammatory syndrome.
AIDS reviews, 2003The use of highly active antiretroviral therapy (HAART) has led to a substantial decrease in the frequency of opportunistic infections among HIV-infected individuals, along with a significant reduction in their mortality rate. However, a subgroup of HAART-treated patients will exhibit paradoxical deterioration in their clinical status, despite ...
Samuel A, Shelburne, Richard J, Hamill
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