Results 251 to 260 of about 292,750 (306)

Cytokines in Immunity and Allograft Rejection

Critical Reviews™ in Immunology, 2002
Cytokines are highly potent regulatory molecules that are secreted by a variety of cells into the local microenvironment. These chemical messengers participate in the activation and regulation of immune function by a variety of mechanisms, including the stimulation and inhibition of cellular proliferation and differentiation.
Louis C, Benjamin, James S, Allan, Joren C, Madsen   +2 more
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Chronic rejection failure of immune regulation

Frontiers in Bioscience, 2003
Current strategies for immunosuppression following organ transplantation focus on the prevention of acute rejection. As new generations of immunosuppressants have been developed, acute rejection rates have diminished markedly. The new challenge, then, is to prevent the devastating complications of chronic rejection, which have remained largely ...
Jeremy, Goodman, Thalachallour, Mohanakumar   +1 more
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Uric Acid Promotes Tumor Immune Rejection

Cancer Research, 2004
Abstract Uric acid released from dying cells has been shown recently to act as a danger signal for the immune system, stimulating dendritic cell maturation and enhancing T-cell responses to foreign antigens. Stimulation of dendritic cell maturation by uric acid has been proposed as a mechanism by which the immune system could generate ...
De-En, Hu, Alistair M, Moore, Lindy L, Thomsen, Kevin M, Brindle   +3 more
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Immune Mechanisms of Lung Allograft Rejection

Seminars in Respiratory and Critical Care Medicine, 2006
Extended survival after lung transplantation is primarily limited by progressive airflow obstruction and fibrotic obliteration of the small airways, termed bronchiolitis obliterans syndrome (BOS) and bronchiolitis obliterans (BO), respectively. BO is thought to represent the pulmonary-specific manifestation of chronic allograft rejection and the end ...
Laurie D, Snyder, Scott M, Palmer
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Acute rejection on immune-mediated chronic rejection after liver transplantation

Gazzetta Medica Italiana Archivio per le Scienze Mediche, 2021
Rejection is frequent after liver transplantation (LT). Pathogenesis of acute cellular rejection (ACR) is attributable to recipient Tcells; chronic rejection (CR) has a multifactorial pathogenesis. There is a striking increase in LTamong women of reproductive age.
D'AMBROSIO D., TAVANO D., LATTANZI B., FRAMARINODEIMALATESTA M., DEVILLEDEGOYET J., CORSI A., MITTERHOFER A. P., GINANNICORRADINI S., MENNINI G., ROSSI M., MERLI M.   +10 more
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Electrochemical Modification of Hyperacute Immune Rejection

European Surgical Research, 1973
A heterotopic liver experiment was set up in which a force field was applied to the transplanted liver.
P N, Sawyer, R, Rubin, B, Stanczewski, A, Parmeggiani, M, Costello, T R, Lucas, S, Srinivasan   +6 more
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Fetal rejection: infertility and immunity

Expert Review of Clinical Immunology, 2007
Defective reaction toward fetal alloantigens could result in both recurrent spontaneous abortions (RSAs) and recurrent early pregnancy failures (REPFs), the latter existing in couples with unexplained infertility and multiple failures of implantation after in vitro fertilization embryo transfer.
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Corneal Immune Rings Associated With Heterograft Rejection

Archives of Ophthalmology, 1965
It has been shown experimentally that the cornea is capable of supporting two types of hypersensitivity phenomena. 1 The first type appears to be mediated by immunologically competent mononuclear cells, the second type by circulating antibodies. When a soluble protein antigen is used to sensitize the cornea, the cellular-mediated response is manifest ...
J H, ELLIOTT, H M, LEIBOWITZ
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Immune-Mediated Tumor Rejection

2010
Fundamental strides in the understanding of the molecular basis of tumor rejection were made in the last decade thanks to observational studies performed at relevant time points in human cancerous tissues. The following concepts emerged: immune surveillance against tumors is a likely occurrence.
Ena Wang, Francesco M. Marincola
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Innate immunity in transplant tolerance and rejection

Immunological Reviews, 2011
Summary:  Historically, research on transplant rejection and tolerance has focused on cells of the adaptive immune system, especially T cells. Anti‐graft effector T cells are necessary and sufficient for the rejection of most allografts, while regulatory T cells, either arising naturally or as a result of a specific treatment regimen, are crucial to ...
Shaun P, Murphy, Paige M, Porrett, Laurence A, Turka   +2 more
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