Results 161 to 170 of about 12,660,283 (403)
Colubrid Venom Composition: An -Omics Perspective
Toxins, 2016 Snake venoms have been subjected to increasingly sensitive analyses for well over 100 years, but most research has been restricted to front-fanged snakes, which actually represent a relatively small proportion of extant species of advanced snakes ...
Inácio L. M. Junqueira-de-Azevedo +3 more
doaj +1 more source
A branching network model for T cell dissemination in adaptive immune response [PDF]
, 2015 Alessandro Boianelli, Antonio Vicino
openalex +1 more source
Foreign Body Reaction (Immune Response) for Artificial Implants Can Be Avoided: An Example of Polyurethane in Mice for 1 Week [PDF]
, 2023 Irina Kondyurina, Alexey Kondyurin
openalex +1 more source
Cancer stemness, intratumoral heterogeneity, and immune response across cancers
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance The exclusion of immune cells from the tumor microenvironment has been associated with poor prognosis in the majority of cancers. We report that when considering 21 solid cancer types, immune cell exclusion is widely associated with the ...
A. Miranda +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Castanea crenata honey reduces influenza infection by activating the innate immune response [PDF]
, 2023 Eun‐Bin Kwon +7 more
openalex +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
TRP Family Genes Are Differently Expressed and Correlated with Immune Response in Glioma [PDF]
, 2022 Chaoyou Fang +10 more
openalex +1 more source
A single-cell atlas of the peripheral immune response in patients with severe COVID-19
Nature Medicine, 2020 Aaron J. Wilk +14 more
semanticscholar +1 more source